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Colq
Gene Detail
 Symbol
Name
ID
Colq
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
MGI:1338761
Feature Type protein coding gene
Genetic Map
Chromosome 14
19.18 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:31523082-31591343 bp, - strand
From VEGA annotation of GRCm38

  68262 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10437  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Colq

Human
homologs
Human Homolog COLQ, collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
NCBI Gene ID 8292
neXtProt AC  NX_Q9Y215
Human Synonyms  EAD
Human Chr (Location)  3p25; chr3:15450133-15521751 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human COLQ
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit tremors, reduced body weight, lack of asymmetric forms of acetylcholinesterase and butyrylcholinesterase, and lethality prior to maturation.
 
Phenotype Images(2)
Interactions
Colq interacts with 194 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process neurotransmitter catabolic process
Component cell junction, collagen trimer, ...
Function heparin binding
External Resources: FuncBase
Expression
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000033849 (Evidence)
Ensembl Gene ModelENSMUSG00000057606 (Evidence)
Entrez Gene382864 (Evidence)
UniGene239821
DFCITC1595376, TC1603115, TC1651724
DoTSDT.60104401, DT.91388333
NIA Mouse Gene IndexU041456
Consensus CDS ProjectCCDS36856.2
International Mouse Knockout Project StatusColq
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033849 VEGA Gene Model | MGI Sequence Detail 68262 C57BL/6J ±  kb
transcript OTTMUST00000085298 VEGA | MGI Sequence Detail 2837 Not Applicable 
polypeptide OTTMUSP00000046070 VEGA | MGI Sequence Detail 457 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(313 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008160 Collagen triple helix repeat
InterPro IPR011936 Myxococcus cysteine-rich repeat
Protein Ontology PR:000005728 acetylcholinesterase collagenic tail peptide
References (Earliest) J:54000 Krejci E, et al., The mammalian gene of acetylcholinesterase-associated collagen. J Biol Chem. 1997 Sep 5;272(36):22840-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory