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Rab33b
Gene Detail
Symbol

Name
ID
Rab33b
RAB33B, member RAS oncogene family
MGI:1330805
Feature Type
protein coding gene
Genetic Map
Chromosome 3
22.49 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:51483920-51496232 bp, + strand
From VEGA annotation of GRCm38

  12313 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9642  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAB33B
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab33b

Human
homologs
RAB33B, RAB33B, member RAS oncogene family
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 83452
neXtProt AC: NX_Q9H082

Human Synonyms: SMC2

Human Chr (Location): 4q28; chr4:139453232-139475916 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RAB33B

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , CvDC )
Interactions
Rab33b interacts with 265 markers (Mir7-2, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process autophagy, intracellular protein transport, ...
Component extracellular exosome, Golgi apparatus, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
cDNA source data(56)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab33b    NEW 
Molecular
reagents
All nucleic(56) cDNA(56)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000051613 (Evidence)
Ensembl Gene Model ENSMUSG00000027739 (Evidence)
Entrez Gene 19338 (Evidence)
UniGene 1664
DFCI TC1575030
DoTS DT.486808, DT.101304196
NIA Mouse Gene Index U003216
PDB 2G77, 1Z06
Consensus CDS Project CCDS38427.1
International Mouse Phenotyping Consortium Status Rab33b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051613 VEGA Gene Model | MGI Sequence Detail 12313 C57BL/6J ±  kb
transcript OTTMUST00000069820 VEGA | MGI Sequence Detail 3492 Not Applicable 
polypeptide OTTMUSP00000035514 VEGA | MGI Sequence Detail 229 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(42 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013609 ras-related protein Rab-33B
References
(Earliest) J:52723 Zheng JY, et al., A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae. J Cell Sci. 1998 Apr;111(Pt 8):1061-9
(Latest) J:190086 Itoh T, et al., Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell. 2008 Jul;19(7):2916-25
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory