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Hnrnpab
Gene Detail
 Symbol
Name
ID
Hnrnpab
heterogeneous nuclear ribonucleoprotein A/B
MGI:1330294
Synonyms CBF-A, Cgbfa, Hnrpab
Feature Type protein coding gene
Genetic Map
Chromosome 11
31.11 cM, cytoband B1.3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:51600100-51606847 bp, - strand
From VEGA annotation of GRCm38

  6748 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74950  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 chicken; 2 zebrafish

Gene Tree: Hnrnpab

Human
homologs
Human Homolog HNRNPAB, heterogeneous nuclear ribonucleoprotein A/B
NCBI Gene ID 3182
neXtProt AC  NX_Q99729
Human Synonyms  ABBP1, HNRPAB
Human Chr (Location)  5q35.3; chr5:178204507-178211183 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(25) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hnrnpab interacts with 264 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process epithelial to mesenchymal transition, negative regulation of transcription from RNA polymerase II promoter, ...
Component cytoplasm, nucleus, ...
Function DNA binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (106)    Tissues (77)    Images (16)
Theiler Stages: 15, 17, 19, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 104
RT-PCR 2
cDNA source data(20)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(23) cDNA(21) Primer pair(1) Other(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000005602 (Evidence)
Ensembl Gene ModelENSMUSG00000020358 (Evidence)
Entrez Gene15384 (Evidence)
Consensus CDS ProjectCCDS24654.1, CCDS48787.1
International Mouse Knockout Project StatusHnrnpab
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005602 VEGA Gene Model | MGI Sequence Detail 6748 C57BL/6J ±  kb
transcript OTTMUST00000012465 VEGA | MGI Sequence Detail 1437 Not Applicable 
polypeptide OTTMUSP00000005764 VEGA | MGI Sequence Detail 332 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(4) UniProt(7)
Polymorphisms SNPs within 2kb(25 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012956 CARG-binding factor, N-terminal
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000008661 heterogeneous nuclear ribonucleoprotein A/B
References (Earliest) J:32624 Tucker PW, et al., Mouse immunoglobulin D: messenger RNA and genomic DNA sequences. Science. 1980 Sep 19;209(4463):1353-60
(Latest) J:203763 Fukuda N, et al., The transacting factor CBF-A/Hnrnpab binds to the A2RE/RTS element of protamine 2 mRNA and contributes to its translational regulation during mouse spermatogenesis. PLoS Genet. 2013;9(10):e1003858
All references(43)
Other
accession IDs
MGI:1890913

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory