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Cox7a1
Gene Detail
Symbol

Name
ID
Cox7a1
cytochrome c oxidase subunit VIIa 1
MGI:1316714
Synonyms
COX7A, COX7AH, COX7AH, COX7AM
Feature Type
protein coding gene
Genetic Map
Chromosome 7
17.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:30184171-30186028 bp, + strand
From Ensembl annotation of GRCm38

  1858 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48051  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: COX7A1
Protein SuperFamily: cytochrome-c oxidase chain VIIa
Gene Tree: Cox7a1

Human
homologs
COX7A1, cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 1346
neXtProt AC: NX_P24310

Human Synonyms: COX7A, COX7AH, COX7AM

Human Chr (Location): 19q13.1; chr19:36150922-36152869 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(7) Targeted(3)
 
Mice homozygous for a knock-out allele exhibit some premature death and dilated cardiomyopathy.
 
Interactions
Cox7a1 interacts with 8 markers (Mir103-1, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (9 records)
Data Summary: Results (14)    Tissues (14)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 12
RT-PCR 2
cDNA source data(72)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100491395    NEW 
Molecular
reagents
All nucleic(74) cDNA(72) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000074218 (Evidence)
Entrez Gene 12865 (Evidence)
UniGene 423030
DFCI TC1578582
DoTS DT.99857018
NIA Mouse Gene Index U350359
Consensus CDS Project CCDS21081.1
International Mouse Phenotyping Consortium Status Cox7a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074218 Ensembl Gene Model | MGI Sequence Detail 1858 C57BL/6J ±  kb
transcript ENSMUST00000098594 Ensembl | MGI Sequence Detail 364 Not Applicable 
polypeptide ENSMUSP00000096193 Ensembl | MGI Sequence Detail 80 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(2) UniProt(2)
Polymorphisms
PCR(1) : SNPs within 2kb(75 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003177 Cytochrome c oxidase, subunit VIIa
Protein Ontology PR:000005786 cytochrome c oxidase subunit 7A1, mitochondrial
References
(Earliest) J:47941 Jaradat SA, et al., Tissue-specific expression and mapping of the Cox7ah gene in mouse (Erratum: 1998;54(3):583-4). Genomics. 1998 May 1;49(3):363-70
(Latest) J:220108 Marotta P, et al., The paired box transcription factor Pax8 is essential for function and survival of adult thyroid cells. Mol Cell Endocrinol. 2014 Oct;396(1-2):26-36
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory