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Cox7a1
Gene Detail
 Symbol
Name
ID
Cox7a1
cytochrome c oxidase subunit VIIa 1
MGI:1316714
Synonyms COX7A, COX7AH, COX7AH, COX7AM
Feature Type protein coding gene
Genetic Map
Chromosome 7
17.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:30184171-30186028 bp, + strand
From Ensembl annotation of GRCm38

  1858 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:48051  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 dog

Protein SuperFamily: cytochrome-c oxidase chain VIIa
Gene Tree: Cox7a1

Human
homologs
Human Homolog COX7A1, cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
NCBI Gene ID 1346
neXtProt AC  NX_P24310
Human Synonyms  COX7A, COX7AH, COX7AM
Human Chr (Location)  19q13.1; chr19:36150922-36152869 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
 
Mice homozygous for a knock-out allele exhibit some premature death and dilated cardiomyopathy.
 
Interactions
Cox7a1 interacts with 8 markers (Mir103-1, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process hydrogen ion transmembrane transport, oxidation-reduction process
Component integral component of membrane, membrane, ...
Function cytochrome-c oxidase activity, electron carrier activity
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (14)    Tissues (14)    Images (1)
Theiler Stages: 10, 18, 21, 23, 24, 25, 28
Assay TypeResults
Northern blot 12
RT-PCR 2
cDNA source data(72)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(74) cDNA(72) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000074218 (Evidence)
Entrez Gene12865 (Evidence)
UniGene423030
DFCITC1578582
DoTSDT.99857018
NIA Mouse Gene IndexU350359
Consensus CDS ProjectCCDS21081.1
International Mouse Knockout Project StatusCox7a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074218 Ensembl Gene Model | MGI Sequence Detail 1858 C57BL/6J ±  kb
transcript ENSMUST00000098594 Ensembl | MGI Sequence Detail 364 Not Applicable 
polypeptide ENSMUSP00000096193 Ensembl | MGI Sequence Detail 80 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(2) UniProt(2)
Polymorphisms PCR(1) : SNPs within 2kb(75 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003177 Cytochrome c oxidase, subunit VIIa
Protein Ontology PR:000005786 cytochrome c oxidase subunit 7A1, mitochondrial
References (Earliest) J:47941 Jaradat SA, et al., Tissue-specific expression and mapping of the Cox7ah gene in mouse (Erratum: 1998;54(3):583-4). Genomics. 1998 May 1;49(3):363-70
(Latest) J:204551 Park JH, et al., A multifunctional protein, EWS, is essential for early brown fat lineage determination. Dev Cell. 2013 Aug 26;26(4):393-404
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory