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Fmo1 Gene Detail
Summary
  • Symbol
    Fmo1
  • Name
    flavin containing monooxygenase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1310002
    NCBI Gene: 14261
  • Alliance
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162829561-162866548 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 70.34 cM, cytoband H1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    297 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1310002
protein coding gene Chr1:162829561-162866610 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016665
protein coding gene Chr1:168184760-168228422 (-)
A/J MGP_AJ_G0016646
protein coding gene Chr1:161341855-161372275 (-)
AKR/J MGP_AKRJ_G0016612
protein coding gene Chr1:166218027-166259980 (-)
BALB/cJ MGP_BALBcJ_G0016607
protein coding gene Chr1:161850726-161880793 (-)
C3H/HeJ MGP_C3HHeJ_G0016431
protein coding gene Chr1:166424090-166457776 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017068
protein coding gene Chr1:173831893-173869221 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014777
protein coding gene Chr1:153374625-153407427 (-)
CAST/EiJ MGP_CASTEiJ_G0016011
protein coding gene Chr1:166075396-166109792 (-)
CBA/J MGP_CBAJ_G0016406
protein coding gene Chr1:180036011-180079235 (-)
DBA/2J MGP_DBA2J_G0016512
protein coding gene Chr1:160266903-160297173 (-)
FVB/NJ MGP_FVBNJ_G0016510
protein coding gene Chr1:158704401-158735372 (-)
LP/J MGP_LPJ_G0016583
protein coding gene Chr1:169293603-169326394 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016535
protein coding gene Chr1:187542038-187575249 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017104
protein coding gene Chr1:166050536-166084119 (-)
PWK/PhJ MGP_PWKPhJ_G0015797
protein coding gene Chr1:159454130-159484425 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015584
protein coding gene Chr1:164941607-164975517 (-)
WSB/EiJ MGP_WSBEiJ_G0016073
protein coding gene Chr1:166234298-166264136 (-)



Homology
more
  • Human Ortholog
    FMO1, flavin containing monooxygenase 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    FMO1, flavin containing monooxygenase 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2326
    neXtProt AC: NX_Q01740
    UniProt: Q01740

  • Chr Location
    1q24.3; chr1:171248471-171285978 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14261 NCBI Gene Model | MGI Sequence Detail 36988 C57BL/6J ±  kb
transcript NM_010231 RefSeq | MGI Sequence Detail 2404 C57BL/6  
polypeptide P50285 UniProt | EBI | MGI Sequence Detail 532 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 116
    cDNA 116

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:28615 Falls JG, et al., Gender differences in hepatic expression of flavin-containing monooxygenase isoforms (FMO1, FMO3, and FMO5) in mice. J Biochem Toxicol. 1995 Jun;10(3):171-7
  • Latest
    J:254969 Huang X, et al., Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling. Elife. 2017 Nov 23;6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory