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Fmo1 Gene Detail
Summary
  • Symbol
    Fmo1
  • Name
    flavin containing monooxygenase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1310002
    NCBI Gene: 14261
Location & Maps
more
  • Sequence Map
    Chr1:162829561-162866610 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      37050 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 70.34 cM, cytoband H1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    FMO1, flavin containing monooxygenase 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    FMO1, flavin containing monooxygenase 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2326
    neXtProt AC: NX_Q01740

  • Chr Location
    1q24.3; chr1:171248471-171285978 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Fmo1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024069 VEGA Gene Model | MGI Sequence Detail 37050 C57BL/6J ±  kb
transcript OTTMUST00000058842 VEGA | MGI Sequence Detail 2388 Not Applicable  
polypeptide OTTMUSP00000028565 VEGA | MGI Sequence Detail 532 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    298 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 115
    cDNA 115

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:28615 Falls JG, et al., Gender differences in hepatic expression of flavin-containing monooxygenase isoforms (FMO1, FMO3, and FMO5) in mice. J Biochem Toxicol. 1995 Jun;10(3):171-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory