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Gstm5 Gene Detail
Summary
  • Symbol
    Gstm5
  • Name
    glutathione S-transferase, mu 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1309466
    NCBI Gene: 14866
  • Gene Overview
    MyGene.info: GSTM3
Location & Maps
more
  • Sequence Map
    Chr3:107895821-107898686 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2866 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.83 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GSTM3, glutathione S-transferase mu 3 (brain)
  • Vertebrate Orthologs
    11
  • Human Ortholog
    GSTM3, glutathione S-transferase mu 3 (brain)
    Orthology source: HomoloGene
  • Synonyms
    GST5, GSTB, GSTM3-3, GTM3
  • Links
    NCBI Gene ID: 2947
    neXtProt AC: NX_P21266

  • Chr Location
    1p13.3; chr1:109733932-109741038 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Gstm5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035923 VEGA Gene Model | MGI Sequence Detail 2866 C57BL/6J ±  kb
transcript OTTMUST00000092142 VEGA | MGI Sequence Detail 945 Not Applicable  
polypeptide OTTMUSP00000050854 VEGA | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    69 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • EC
  • InterPro Domains
    IPR004046 Glutathione S-transferase, C-terminal
    IPR010987 Glutathione S-transferase, C-terminal-like
    IPR003081 Glutathione S-transferase, Mu class
    IPR004045 Glutathione S-transferase, N-terminal
    IPR012336 Thioredoxin-like fold
Molecular
Reagents
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  • All nucleic 260
    cDNA 259
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 33
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:30024 Fulcher KD, et al., Identification of a unique mu-class glutathione S-transferase in mouse spermatogenic cells. Mol Reprod Dev. 1995 Dec;42(4):415-24
  • Latest
    J:197340 Chung C, et al., Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7732-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory