Cyp2c38
Gene Detail

Symbol Name ID

Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 MGI:1306819

Feature Type

protein coding gene

Genetic Map

Chromosome 19

34.03 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:39389556-39463075 bp, - strand From VEGA annotation of GRCm38   73520 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:117948  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 chicken

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c38

Human homologs

Human Homolog		CYP2C8, cytochrome P450, family 2, subfamily C, polypeptide 8
NCBI Gene ID		1558
neXtProt AC		NX_P10632
Human Synonyms		CPC8, CYPIIC8, MP-12/MP-20
Human Chr (Location)		10q23.33; chr10:96796529-96829254 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP2C8

Alleles and phenotypes

All alleles(1) : Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	aromatase activity, caffeine oxidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(7) Primer pair(1) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000028396 (Evidence)
Ensembl Gene Model	ENSMUSG00000032808 (Evidence)
Entrez Gene	13097 (Evidence)
UniGene	42100
DFCI	TC1590601
DoTS	DT.91336067
NIA Mouse Gene Index	U143916
EC	1.14.14.1
Consensus CDS Project	CCDS29794.1
International Mouse Knockout Project Status	Cyp2c38

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028396	VEGA Gene Model | MGI Sequence Detail	73520	C57BL/6J
transcript	OTTMUST00000070360	VEGA | MGI Sequence Detail	2869	Not Applicable
polypeptide	OTTMUSP00000035844	VEGA | MGI Sequence Detail	490	Not Applicable

All sequences(18) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(216 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
Protein Ontology	PR:000006227	cytochrome P450 2C38

References

(Earliest) J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(28)