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Pcdha10 Gene Detail
Summary
  • Symbol
    Pcdha10
  • Name
    protocadherin alpha 10
  • Synonyms
    Cnr3, Cnr8, Crnr3, Crnr8, Pcdha14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298408
    NCBI Gene: 12943
  • Member of
    Pcdha cluster
  • Gene Overview
    MyGene.info: PCDHA12
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:37005320-37187657 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.46 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1247 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298408
protein coding gene Chr18:37005320-37187657 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PCDHA12, protocadherin alpha 12
  • Vertebrate Orthologs
    4
  • Human Ortholog
    PCDHA12, protocadherin alpha 12
    Orthology source: HomoloGene
  • Synonyms
    PCDH-ALPHA12
  • Links
    NCBI Gene ID: 56137
    neXtProt AC: NX_Q9UN75
    UniProt: Q9UN75

  • Chr Location
    5q31.3; chr5:140875302-141012344 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12943 NCBI Gene Model | MGI Sequence Detail 182338 C57BL/6J ±  kb
transcript NM_009961 RefSeq | MGI Sequence Detail 5242 Not Specified  
polypeptide Q91Y20 UniProt | EBI | MGI Sequence Detail 946 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 11
    Genomic 3
    cDNA 5
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1298368
References
more
  • Summaries
    All 26
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:48282 Kohmura N, et al., Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 1998 Jun;20(6):1137-51
  • Latest
    J:277192 Shao Z, et al., Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nat Neurosci. 2019 Feb;22(2):229-242

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory