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Pcdha11 Gene Detail
Summary
  • Symbol
    Pcdha11
  • Name
    protocadherin alpha 11
  • Synonyms
    A830022B16Rik, Cnr7, Crnr7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298372
    NCBI Gene: 12942
  • Member of
    Pcdha cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37010858-37187657 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.46 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1188 from dbSNP Build 142
  • Strain Annotations
    35
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298372
protein coding gene Chr18:37005203-37187657 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024306
protein coding gene Chr18:35416805-35583235 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024305
protein coding gene Chr18:35411298-35583235 (+)
A/J MGP_AJ_G0024272
protein coding gene Chr18:34182214-34357515 (+)
A/J MGP_AJ_G0024273
protein coding gene Chr18:34188410-34357515 (+)
AKR/J MGP_AKRJ_G0024240
protein coding gene Chr18:35144318-35313391 (+)
AKR/J MGP_AKRJ_G0024241
protein coding gene Chr18:35149821-35313391 (+)
BALB/cJ MGP_BALBcJ_G0024271
protein coding gene Chr18:34232213-34406362 (+)
BALB/cJ MGP_BALBcJ_G0024272
protein coding gene Chr18:34237717-34406362 (+)
C3H/HeJ MGP_C3HHeJ_G0024038
protein coding gene Chr18:35196623-35358175 (+)
C3H/HeJ MGP_C3HHeJ_G0024039
protein coding gene Chr18:35202127-35358175 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024713
protein coding gene Chr18:36677068-36867648 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024714
protein coding gene Chr18:36684233-36867648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022152
protein coding gene Chr18:34269436-34436126 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022153
protein coding gene Chr18:34274944-34436126 (+)
CAST/EiJ MGP_CASTEiJ_G0023513
protein coding gene Chr18:35197000-35356123 (+)
CAST/EiJ MGP_CASTEiJ_G0023514
protein coding gene Chr18:35204641-35356123 (+)
CBA/J MGP_CBAJ_G0024007
protein coding gene Chr18:37761497-37945878 (+)
CBA/J MGP_CBAJ_G0024008
protein coding gene Chr18:37769039-37945878 (+)
DBA/2J MGP_DBA2J_G0024139
protein coding gene Chr18:33806323-33963728 (+)
DBA/2J MGP_DBA2J_G0024138
protein coding gene Chr18:33800898-33963728 (+)
FVB/NJ MGP_FVBNJ_G0024105
protein coding gene Chr18:33518628-33689539 (+)
FVB/NJ MGP_FVBNJ_G0024104
protein coding gene Chr18:33513228-33689539 (+)
LP/J MGP_LPJ_G0024221
protein coding gene Chr18:35483963-35676922 (+)
LP/J MGP_LPJ_G0024222
protein coding gene Chr18:35491646-35676922 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024133
protein coding gene Chr18:39013455-39218915 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024134
protein coding gene Chr18:39018959-39218915 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024762
protein coding gene Chr18:35010883-35180644 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024763
protein coding gene Chr18:35016394-35180644 (+)
PWK/PhJ MGP_PWKPhJ_G0023258
protein coding gene Chr18:34043637-34203479 (+)
PWK/PhJ MGP_PWKPhJ_G0023259
protein coding gene Chr18:34050145-34203479 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023062
protein coding gene Chr18:35261581-35441752 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023063
protein coding gene Chr18:35269562-35441752 (+)
WSB/EiJ MGP_WSBEiJ_G0023576
protein coding gene Chr18:34914838-35081773 (+)
WSB/EiJ MGP_WSBEiJ_G0023577
protein coding gene Chr18:34920353-35081773 (+)



Homology
more
  • Human Ortholog
    PCDHA11, protocadherin alpha 11
  • Vertebrate Orthologs
    4
  • Human Ortholog
    PCDHA11, protocadherin alpha 11
    Orthology source: HomoloGene
  • Synonyms
    CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11
  • Links
    NCBI Gene ID: 56138
    neXtProt AC: NX_Q9Y5I1
    UniProt: Q9Y5I1

  • Chr Location
    5q31.3; chr5:140867513-141012344 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12942 NCBI Gene Model | MGI Sequence Detail 176800 C57BL/6J ±  kb
transcript NM_009960 RefSeq | MGI Sequence Detail 5254 Not Specified  
polypeptide NP_034090 RefSeq | MGI Sequence Detail 950 Not Specified  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 15
    Genomic 3
    cDNA 10
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444164
References
more
  • Summaries
    All 28
    Developmental Gene Expression 6
    Gene Ontology 3
  • Earliest
    J:48282 Kohmura N, et al., Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 1998 Jun;20(6):1137-51
  • Latest
    J:264145 Fan L, et al., Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice. Elife. 2018 Jun 18;7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory