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Pcdha5 Gene Detail
Summary
  • Symbol
    Pcdha5
  • Name
    protocadherin alpha 5
  • Synonyms
    Cnr6, Crnr6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298371
    NCBI Gene: 12941
  • Member of
    Pcdha cluster
  • Gene Overview
    MyGene.info: PCDHA5
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:36960440-37187657 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1817 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298371
protein coding gene Chr18:36960440-37187657 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024299
protein coding gene Chr18:35373735-35583235 (+)
A/J MGP_AJ_G0024265
protein coding gene Chr18:34136539-34357515 (+)
AKR/J MGP_AKRJ_G0024233
protein coding gene Chr18:35107437-35313391 (+)
BALB/cJ MGP_BALBcJ_G0024265
protein coding gene Chr18:34184557-34406362 (+)
C3H/HeJ MGP_C3HHeJ_G0024032
protein coding gene Chr18:35154937-35358175 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024706
protein coding gene Chr18:36619213-36867648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022146
protein coding gene Chr18:34231684-34436126 (+)
CAST/EiJ MGP_CASTEiJ_G0023507
protein coding gene Chr18:35156182-35356123 (+)
CBA/J MGP_CBAJ_G0024000
protein coding gene Chr18:37702352-37945878 (+)
DBA/2J MGP_DBA2J_G0024132
protein coding gene Chr18:33751265-33963728 (+)
FVB/NJ MGP_FVBNJ_G0024098
protein coding gene Chr18:33465330-33689539 (+)
LP/J MGP_LPJ_G0024215
protein coding gene Chr18:35422823-35676922 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024127
protein coding gene Chr18:38951334-39218915 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024755
protein coding gene Chr18:34960775-35180644 (+)
PWK/PhJ MGP_PWKPhJ_G0023251
protein coding gene Chr18:33993492-34203479 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023059
protein coding gene Chr18:35235106-35441752 (+)
WSB/EiJ MGP_WSBEiJ_G0023570
protein coding gene Chr18:34871116-35081773 (+)



Homology
more
  • Human Ortholog
    PCDHA5, protocadherin alpha 5
  • Vertebrate Orthologs
    6
  • Human Ortholog
    PCDHA5, protocadherin alpha 5
    Orthology source: HomoloGene
  • Synonyms
    CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
  • Links
    NCBI Gene ID: 56143
    neXtProt AC: NX_Q9Y5H7
    UniProt: Q9Y5H7

  • Chr Location
    5q31.3; chr5:140821776-141012344 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12941 NCBI Gene Model | MGI Sequence Detail 227218 C57BL/6J ±  kb
transcript NM_009959 RefSeq | MGI Sequence Detail 5206 Not Specified  
polypeptide NP_034089 RefSeq | MGI Sequence Detail 934 Not Specified  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 4
    Primer pair 1
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 5
    Gene Ontology 3
  • Earliest
    J:48282 Kohmura N, et al., Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 1998 Jun;20(6):1137-51
  • Latest
    J:264145 Fan L, et al., Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice. Elife. 2018 Jun 18;7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory