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Pcdha7 Gene Detail
Summary
  • Symbol
    Pcdha7
  • Name
    protocadherin alpha 7
  • Synonyms
    Cnr4, Crnr4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298369
    NCBI Gene: 12939
  • Member of
    Pcdha cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:36973924-37187657 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1590 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298369
protein coding gene Chr18:36973802-37187657 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024302
protein coding gene Chr18:35386624-35583235 (+)
A/J MGP_AJ_G0024268
protein coding gene Chr18:34150379-34357515 (+)
AKR/J MGP_AKRJ_G0024236
protein coding gene Chr18:35120398-35313391 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0024709
protein coding gene Chr18:36640390-36867648 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0023510
protein coding gene Chr18:35172608-35356123 (+)
CBA/J MGP_CBAJ_G0024003
protein coding gene Chr18:37719561-37945878 (+)
DBA/2J MGP_DBA2J_G0024135
protein coding gene Chr18:33765808-33963728 (+)
FVB/NJ MGP_FVBNJ_G0024101
protein coding gene Chr18:33478084-33689539 (+)
LP/J MGP_LPJ_G0024217
protein coding gene Chr18:35429018-35676922 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024130
protein coding gene Chr18:38965926-39218915 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024758
protein coding gene Chr18:34975346-35180644 (+)
PWK/PhJ MGP_PWKPhJ_G0023254
protein coding gene Chr18:34008791-34203479 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0023573
protein coding gene Chr18:34885058-35081773 (+)



Homology
more
  • Human Ortholog
    PCDHA7, protocadherin alpha 7
  • Vertebrate Orthologs
    5
  • Human Ortholog
    PCDHA7, protocadherin alpha 7
    Orthology source: HomoloGene
  • Synonyms
    CNR4, CNRN4, CNRS4, CRNR4, PCDH-ALPHA7
  • Links
    NCBI Gene ID: 56141
    neXtProt AC: NX_Q9UN72
    UniProt: Q9UN72

  • Chr Location
    5q31.3; chr5:140834384-141012344 (+)  GRCh38.p7

Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12939 NCBI Gene Model | MGI Sequence Detail 213734 C57BL/6J ±  kb
transcript NM_009957 RefSeq | MGI Sequence Detail 5334 C57BL/6  
polypeptide Q91Y13 UniProt | EBI | MGI Sequence Detail 937 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    Genomic 2
    cDNA 6
    Primer pair 1
    Other 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 7
    Gene Ontology 6
  • Earliest
    J:48282 Kohmura N, et al., Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex. Neuron. 1998 Jun;20(6):1137-51
  • Latest
    J:264145 Fan L, et al., Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice. Elife. 2018 Jun 18;7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory