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Ccdc39
Gene Detail
Symbol

Name
ID
Ccdc39
coiled-coil domain containing 39
MGI:1289263
Synonyms
4921507O14Rik, b2b1304Clo, b2b1735Clo, b2b2025.1Clo, D3Ertd789e
Feature Type
protein coding gene
Genetic Map
Chromosome 3
16.32 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:33812362-33844310 bp, - strand
From VEGA annotation of GRCm38

  31949 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12149  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CCDC39
Gene Tree: Ccdc39

Human
homologs
CCDC39, coiled-coil domain containing 39
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 339829
neXtProt AC: NX_Q9UFE4

Human Synonyms: CILD14, FAP59

Human Chr (Location): 3q26.33; chr3:180614008-180679495 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CCDC39

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Chemically induced (ENU)(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Chemically induced mutations in this gene result in situs inversus totalis with dextrocardia, double outlet right ventricle and atrial septal defects, kidney abnormalities including cysts and hydronephrosis, and immotile tracheal airway cilia.
 
Human Diseases Modeled in Mice Using Ccdc39 (1)    Mutations Annotated to Human Diseases (3)    Phenotype Images(43)
Interactions
Ccdc39 interacts with 193 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process axonemal dynein complex assembly, cilium-dependent cell motility, ...
Component axoneme, cell projection, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ccdc39    NEW 
Molecular
reagents
All nucleic(19) cDNA(17) Primer pair(1) Other(1)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000026483 (Evidence)
Ensembl Gene Model ENSMUSG00000027676 (Evidence)
Entrez Gene 51938 (Evidence)
NIA Mouse Gene Index U023926
Consensus CDS Project CCDS17304.1
International Mouse Phenotyping Consortium Status Ccdc39
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026483 VEGA Gene Model | MGI Sequence Detail 31949 C57BL/6J ±  kb
transcript OTTMUST00000065474 VEGA | MGI Sequence Detail 3606 Not Applicable 
polypeptide OTTMUSP00000032639 VEGA | MGI Sequence Detail 937 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(14) UniProt(3)
Polymorphisms
SNPs within 2kb(237 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000032363 coiled-coil domain-containing protein 39
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4
All references(33)
Disease annotation references (1)
Other
accession IDs
MGI:1914785, MGI:2139706, MGI:2139809, MGI:5316773, MGI:5438051, MGI:5554524

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory