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Ncaph2
Gene Detail
Symbol

Name
ID
Ncaph2
non-SMC condensin II complex, subunit H2
MGI:1289164
Synonyms
0610010J20Rik, 2610524G04Rik, D15Ertd785e, Kleisin beta
Feature Type
protein coding gene
Genetic Map
Chromosome 15
44.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:89355719-89372826 bp, + strand
From VEGA annotation of GRCm38

  17108 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12045  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ncaph2

Human
homologs
Human Homolog NCAPH2, non-SMC condensin II complex, subunit H2
NCBI Gene ID 29781
neXtProt AC  NX_Q6IBW4
Human Synonyms  CAPH2
Human Chr (Location)  22q13.33; chr22:50508216-50524780 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(26) : Chemically induced (ENU)(1) Gene trapped(20) Radiation induced(1) Targeted(4)
Genomic Mutations involving Ncaph2 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU-induced single point mutation display a specific defect in T cell development but are otherwise viable, fertile and overtly healthy with no apparent defects in B cell development.
 
Interactions
Ncaph2 interacts with 285 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process chromosome condensation, T cell differentiation in thymus
Component membrane, nucleus
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (25)    Tissues (16)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 25
cDNA source data(24)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) cDNA(25) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000024517 (Evidence)
Ensembl Gene ModelENSMUSG00000008690 (Evidence)
Entrez Gene52683 (Evidence)
Consensus CDS ProjectCCDS49700.1, CCDS70660.1, CCDS70661.1
International Mouse Knockout Project StatusNcaph2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024517 VEGA Gene Model | MGI Sequence Detail 17108 C57BL/6J ±  kb
transcript OTTMUST00000060166 VEGA | MGI Sequence Detail 3302 Not Applicable 
polypeptide OTTMUSP00000029342 VEGA | MGI Sequence Detail 608 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(11) UniProt(4)
Polymorphisms
SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009378 Non-SMC condensin II complex, subunit H2-like
Protein Ontology PR:000011025 condensin-2 complex subunit H2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:195103 Theodoratos A, et al., Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1. FEBS J. 2012 Apr;279(8):1422-32
All references(41)
Other
accession IDs
MGI:1914092, MGI:1919756, MGI:2145963

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory