Ncaph2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ncaph2
non-SMC condensin II complex, subunit H2
MGI:1289164

26 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ncaph2^nes/Ncaph2^nes C57BL/6-Ncaph2^nes	abnormal cerebral cortex morphology	J:242515
	abnormal mitosis	J:242515
	abnormal neocortex size	J:242515
	decreased body weight	J:242515
	decreased brain weight	J:242515
	microcephaly	J:242515
Ncaph2^nes/Ncaph2^nes C57BL/6JSfdAnu-Ncaph2^nes/Anu	abnormal double-negative T cell morphology	J:123300
	abnormal splenic cell ratio	J:123300
	abnormal T cell morphology	J:123300
	abnormal thymus cell ratio	J:123300
	abnormal thymus cortex morphology	J:123300
	abnormal thymus corticomedullary boundary morphology	J:123300
	decreased CD8-positive, alpha-beta T cell number	J:123300
	decreased double-negative T cell number	J:123300
	decreased double-positive T cell number	J:123300
	decreased T cell number	J:123300
	decreased thymocyte number	J:123300
	thymus hypoplasia	J:123300
Ncaph2^tm1.1Hiran/Ncaph2^tm1.2Hiran Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J * SJL	abnormal cell nucleus morphology	J:222181
	abnormal cerebral cortex morphology	J:222181
	abnormal cortical plate morphology	J:222181
	abnormal mitosis	J:222181
	abnormal neuronal stem cell morphology	J:222181
	abnormal neuronal stem cell physiology	J:222181
	abnormal nucleolus morphology	J:222181
	decreased neuron number	J:222181
Ncaph2^tm1.2Hiran/Ncaph2^tm1.2Hiran involves: C57BL/6 * C57BL/6J	embryonic lethality, complete penetrance	J:222181
Ncaph2^{tm1a(EUCOMM)Wtsi}/Ncaph2⁺ B6JTyr;B6N-Ncaph2^{tm1a(EUCOMM)Wtsi}/Wtsi	increased circulating amylase level	J:175295

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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