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Dnpep Gene Detail
Summary
  • Symbol
    Dnpep
  • Name
    aspartyl aminopeptidase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1278328
    NCBI Gene: 13437
  • Gene Overview
    MyGene.info: DNPEP
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:75308565-75317654 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1278328
protein coding gene Chr1:75307896-75317990 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016184
protein coding gene Chr1:75874197-75884295 (-)
A/J MGP_AJ_G0016167
protein coding gene Chr1:73230601-73240696 (-)
AKR/J MGP_AKRJ_G0016124
protein coding gene Chr1:75261015-75271114 (-)
BALB/cJ MGP_BALBcJ_G0016122
protein coding gene Chr1:73291968-73302062 (-)
C3H/HeJ MGP_C3HHeJ_G0015953
protein coding gene Chr1:75596962-75607057 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016575
protein coding gene Chr1:78827059-78837109 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014296
protein coding gene Chr1:68793116-68803511 (-)
CAST/EiJ MGP_CASTEiJ_G0015537
protein coding gene Chr1:74939915-74950038 (-)
CBA/J MGP_CBAJ_G0015926
protein coding gene Chr1:81389792-81399887 (-)
DBA/2J MGP_DBA2J_G0016027
protein coding gene Chr1:72548856-72558954 (-)
FVB/NJ MGP_FVBNJ_G0016030
protein coding gene Chr1:71752138-71762236 (-)
LP/J MGP_LPJ_G0016099
protein coding gene Chr1:76999419-77009517 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016050
protein coding gene Chr1:84739628-84749925 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016622
protein coding gene Chr1:75330621-75340719 (-)
PWK/PhJ MGP_PWKPhJ_G0015324
protein coding gene Chr1:72023009-72033080 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015102
protein coding gene Chr1:74697746-74707835 (-)
WSB/EiJ MGP_WSBEiJ_G0015599
protein coding gene Chr1:75144131-75154230 (-)



Homology
more
  • Human Ortholog
    DNPEP, aspartyl aminopeptidase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNPEP, aspartyl aminopeptidase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ASPEP, DAP
  • Links
    NCBI Gene ID: 23549
    neXtProt AC: NX_Q9ULA0
    UniProt: Q9ULA0

  • Chr Location
    2q35; chr2:219372029-219400022 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6110
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DNPEP
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Dnpep
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13437 NCBI Gene Model | MGI Sequence Detail 9090 C57BL/6J ±  kb
transcript NM_001110831 RefSeq | MGI Sequence Detail 1930 C57BL/6  
polypeptide Q9Z2W0 UniProt | EBI | MGI Sequence Detail 473 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 183
    cDNA 183

    Microarray probesets 7
Other
Accession IDs
less
MGI:2138076
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 23
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:262823 Kasowitz SD, et al., Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. PLoS Genet. 2018 May;14(5):e1007412

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory