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Dnpep Gene Detail
Summary
  • Symbol
    Dnpep
  • Name
    aspartyl aminopeptidase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1278328
    NCBI Gene: 13437
  • Gene Overview
    MyGene.info: DNPEP
Location & Maps
more
  • Sequence Map
    Chr1:75307896-75317990 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10095 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DNPEP, aspartyl aminopeptidase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNPEP, aspartyl aminopeptidase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ASPEP, DAP
  • Links
    NCBI Gene ID: 23549
    neXtProt AC: NX_Q9ULA0

  • Chr Location
    2q35; chr2:219373458-219400017 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6110
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DNPEP
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Dnpep
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048821 VEGA Gene Model | MGI Sequence Detail 10095 C57BL/6J ±  kb
transcript OTTMUST00000124886 VEGA | MGI Sequence Detail 2510 Not Applicable  
polypeptide OTTMUSP00000067850 VEGA | MGI Sequence Detail 475 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    208 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 182
    cDNA 182

    Microarray probesets 7
Other
Accession IDs
less
MGI:2138076
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 22
  • Earliest
    J:48315 Wilk S, et al., Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase. J Biol Chem. 1998 Jun 26;273(26):15961-70
  • Latest
    J:209351 Prashar P, et al., Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory