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Itgb2l Gene Detail
Summary
  • Symbol
    Itgb2l
  • Name
    integrin beta 2-like
  • Synonyms
    5033406G21Rik, pactolus
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277979
    NCBI Gene: 16415
Location & Maps
more
  • Sequence Map
    Chr16:96422288-96443619 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21332 bp   ±  kb flank

  • Genome Browsers
Homology
less
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
  • All Mutations and Alleles
    8
  • Targeted
    8
  • Genomic Mutations
    5 involving Itgb2l
  • Incidental Mutations
Mice homozygous for a null allele display normal leukocyte development and normal neutrophil recruitment to inflamed tissues.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020391 VEGA Gene Model | MGI Sequence Detail 21332 C57BL/6J ±  kb
transcript OTTMUST00000048345 VEGA | MGI Sequence Detail 2806 Not Applicable  
polypeptide OTTMUSP00000022139 VEGA | MGI Sequence Detail 795 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    138 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 4
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923228
References
more
  • Summaries
    All 26
    Diseases 3
    Gene Ontology 2
    Phenotypes 21
  • Earliest
    J:46963 Chen Y, et al., Identification of pactolus, an integrin beta subunit-like cell-surface protein preferentially expressed by cells of the bone marrow. J Biol Chem. 1998 Apr 10;273(15):8711-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory