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Itgb2l
Gene Detail
Symbol

Name
ID
Itgb2l
integrin beta 2-like
MGI:1277979
Synonyms
5033406G21Rik, pactolus
Feature Type
protein coding gene
Genetic Map
Chromosome 16
56.95 cM, cytoband C6
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:96422288-96443619 bp, - strand
From VEGA annotation of GRCm38

  21332 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: integrin, beta subunit
Gene Tree: Itgb2l
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Itgb2l (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele display normal leukocyte development and normal neutrophil recruitment to inflamed tissues.
 
Interactions
Itgb2l interacts with 135 markers (Mir1b, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell adhesion, inflammatory response, ...
Component integral component of membrane, membrane, ...
Function receptor activity
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(12) Genomic(4) cDNA(8)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020391 (Evidence)
Ensembl Gene ModelENSMUSG00000000157 (Evidence)
Entrez Gene16415 (Evidence)
UniGene12872
DFCITC1585231
DoTSDT.110724751, DT.87031564
NIA Mouse Gene IndexU037345
PDB2IUE
Consensus CDS ProjectCCDS28358.1
International Mouse Knockout Project StatusItgb2l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020391 VEGA Gene Model | MGI Sequence Detail 21332 C57BL/6J ±  kb
transcript OTTMUST00000048345 VEGA | MGI Sequence Detail 2806 Not Applicable 
polypeptide OTTMUSP00000022139 VEGA | MGI Sequence Detail 795 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(14) UniProt(2)
Polymorphisms
SNPs within 2kb(138 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015812 Integrin beta subunit
InterPro IPR002369 Integrin beta subunit, N-terminal
InterPro IPR012896 Integrin beta subunit, tail
InterPro IPR016201 Plexin-like fold
InterPro IPR002035 von Willebrand factor, type A
Protein Ontology PR:000009192 integrin beta-2-like protein
References
(Earliest) J:46963 Chen Y, et al., Identification of pactolus, an integrin beta subunit-like cell-surface protein preferentially expressed by cells of the bone marrow. J Biol Chem. 1998 Apr 10;273(15):8711-8
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:1923228

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory