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Itgb2l Gene Detail
Summary
  • Symbol
    Itgb2l
  • Name
    integrin beta 2-like
  • Synonyms
    5033406G21Rik, pactolus
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277979
    NCBI Gene: 16415
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:96422295-96443626 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 56.95 cM, cytoband C6
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277979
protein coding gene Chr16:96422288-96443626 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023086
protein coding gene Chr16:97802650-97825219 (-)
A/J MGP_AJ_G0023054
protein coding gene Chr16:93173946-93195270 (-)
AKR/J MGP_AKRJ_G0023024
protein coding gene Chr16:96037805-96059124 (-)
BALB/cJ MGP_BALBcJ_G0023056
protein coding gene Chr16:93724521-93745841 (-)
C3H/HeJ MGP_C3HHeJ_G0022817
protein coding gene Chr16:96566891-96588211 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023503
protein coding gene Chr16:100902376-100923697 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021005
protein coding gene Chr16:91015780-91037460 (-)
CAST/EiJ MGP_CASTEiJ_G0022337
protein coding gene Chr16:97365804-97387153 (-)
CBA/J MGP_CBAJ_G0022786
protein coding gene Chr16:105259638-105280965 (-)
DBA/2J MGP_DBA2J_G0022920
protein coding gene Chr16:93048778-93070886 (-)
FVB/NJ MGP_FVBNJ_G0022894
protein coding gene Chr16:92221915-92243236 (-)
LP/J MGP_LPJ_G0022990
protein coding gene Chr16:97442762-97464052 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022915
protein coding gene Chr16:109475609-109496934 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023521
protein coding gene Chr16:96574022-96595352 (-)
PWK/PhJ MGP_PWKPhJ_G0022081
protein coding gene Chr16:93341665-93363653 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021911
protein coding gene Chr16:96115235-96136142 (-)
WSB/EiJ MGP_WSBEiJ_G0022387
protein coding gene Chr16:96843144-96864492 (-)



Homology
less
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    29 phenotype references
Mice homozygous for a null allele display normal leukocyte development and normal neutrophil recruitment to inflamed tissues.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 16415 NCBI Gene Model | MGI Sequence Detail 21332 C57BL/6J ±  kb
transcript NM_008405 RefSeq | MGI Sequence Detail 2618 C57BL/6  
polypeptide Q3UV74 UniProt | EBI | MGI Sequence Detail 738 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 4
    cDNA 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923228
References
more
  • Summaries
    All 54
    Diseases 3
    Gene Ontology 4
    Phenotypes 29
  • Earliest
    J:46963 Chen Y, et al., Identification of pactolus, an integrin beta subunit-like cell-surface protein preferentially expressed by cells of the bone marrow. J Biol Chem. 1998 Apr 10;273(15):8711-8
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory