Itgb2l
Gene Detail

Symbol Name ID

Itgb2l integrin beta 2-like MGI:1277979

Synonyms

5033406G21Rik, pactolus

Feature Type

protein coding gene

Genetic Map

Chromosome 16

56.95 cM, cytoband C6
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr16:96422288-96443619 bp, - strand From VEGA annotation of GRCm38   21332 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Protein SuperFamily: integrin, beta subunit
Gene Tree: Itgb2l

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a null allele display normal leukocyte development and normal neutrophil recruitment to inflamed tissues.

 

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	cell adhesion, cell-matrix adhesion, ...
Component	integral to membrane, integrin complex, ...
Function	receptor activity

External Resources: FuncBase

Expression

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) Genomic(4) cDNA(8)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000020391 (Evidence)
Ensembl Gene Model	ENSMUSG00000000157 (Evidence)
Entrez Gene	16415 (Evidence)
UniGene	12872
DFCI	TC1585231
DoTS	DT.110724751, DT.87031564
NIA Mouse Gene Index	U037345
PDB	2IUE
Consensus CDS Project	CCDS28358.1
International Mouse Knockout Project Status	Itgb2l

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020391	VEGA Gene Model | MGI Sequence Detail	21332	C57BL/6J
transcript	OTTMUST00000048345	VEGA | MGI Sequence Detail	2806	Not Applicable
polypeptide	OTTMUSP00000022139	VEGA | MGI Sequence Detail	795	Not Applicable

All sequences(29) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(132 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015439	Integrin beta-2 subunit
InterPro	IPR015812	Integrin beta subunit
InterPro	IPR002369	Integrin beta subunit, N-terminal
InterPro	IPR012896	Integrin beta subunit, tail
InterPro	IPR016201	Plexin-like fold
InterPro	IPR003659	Plexin/semaphorin/integrin
InterPro	IPR002035	von Willebrand factor, type A
Protein Ontology	PR:000009192	integrin beta-2-like protein

References

(Earliest) J:46963 Chen Y, et al., Identification of pactolus, an integrin beta subunit-like cell-surface protein preferentially expressed by cells of the bone marrow. J Biol Chem. 1998 Apr 10;273(15):8711-8
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)

Other accession IDs

MGI:1923228