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Birc5
Gene Detail
 Symbol
Name
ID
Birc5
baculoviral IAP repeat-containing 5
MGI:1203517
Synonyms Api4, survivin, TIAP
Feature Type protein coding gene
Genetic Map
Chromosome 11
82.96 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:117849251-117855743 bp, + strand
From VEGA annotation of GRCm38

  6493 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37450  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Baculoviral IAP repeat-containing protein 5
Gene Tree: Birc5

Human
homologs
Human Homolog BIRC5, baculoviral IAP repeat containing 5
NCBI Gene ID 332
neXtProt AC  NX_O15392
Human Synonyms  API4, EPR-1
Human Chr (Location)  17q25; chr17:78214196-78225635 (+)  GRCh38
Alleles
and
phenotypes
All alleles(15) : Gene trapped(9) Targeted(6)
 
Homozygous null mutants die during early embryonic development.
 
Gene Ontology
(GO)
classifications
All GO classifications: (64 annotations)
Process apoptotic process, cell cycle, ...
Component apical plasma membrane, centriole, ...
Function chaperone binding, cofactor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (31 records)
Data Summary: Results (208)    Tissues (157)    Images (44)
Theiler Stages: 17, 20, 21, 22, 23, 24, 26, 28
Assay TypeResults
Immunohistochemistry 1
RNA in situ 204
RT-PCR 3
cDNA source data(94)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(100) Genomic(1) cDNA(97) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000003737 (Evidence)
Ensembl Gene ModelENSMUSG00000017716 (Evidence)
Entrez Gene11799 (Evidence)
UniGene8552
DFCITC1574988, TC1589405, TC1619492
DoTSDT.101384264, DT.94262897
NIA Mouse Gene IndexU013607
PDB1M4M
Consensus CDS ProjectCCDS25694.1, CCDS25695.1
International Mouse Knockout Project StatusBirc5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003737 VEGA Gene Model | MGI Sequence Detail 6493 C57BL/6J ±  kb
transcript OTTMUST00000008140 VEGA | MGI Sequence Detail 947 Not Applicable 
polypeptide OTTMUSP00000003966 VEGA | MGI Sequence Detail 140 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(5) UniProt(2)
Polymorphisms SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001370 Baculoviral inhibition of apoptosis protein repeat
Protein Ontology PR:000004753 baculoviral IAP repeat-containing protein 5
References (Earliest) J:42738 Tewari M, et al., AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. Cancer Res. 1997 Sep 15;57(18):4063-9
(Latest) J:208881 Jiang ZZ, et al., Survivin is essential for fertile egg production and female fertility in mice. Cell Death Dis. 2014;5:e1154
All references(100)
Other
accession IDs
MGI:1196343

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory