Birc5 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Birc5
baculoviral IAP repeat-containing 5
MGI:1203517

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hr^hr/Hr^hr Tg(KRT14-Birc5)19Gros/0 involves: C3H * C57BL/6 * SKH1	decreased incidence of tumors by UV induction	J:95011
	decreased sensitivity to skin irradiation	J:95011
	increased squamous cell carcinoma incidence	J:95011
Tg(Dct-Birc5)21Gros/0 Tg(Mt1-Hgf)19Lmb/0 involves: C57BL/6 * CBA * FVB/N	decreased cellular sensitivity to ultraviolet irradiation	J:122181
	increased incidence of tumors by UV-induction	J:122181
	increased melanoma incidence	J:122181
	increased metastatic potential	J:122181
	increased skin tumor incidence	J:122181
Tg(KRT14-Birc5)19Gros/0 Trp53^tm1Brd/Trp53⁺ involves: 129S7/SvEvBrd * C3H * C57BL/6	decreased incidence of tumors by chemical induction	J:81530
Tg(KRT14-Birc5)19Gros/0 Trp53^tm1Brd/Trp53⁺ involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6NCr	abnormal skin condition	J:93483
	decreased sensitivity to skin irradiation	J:93483

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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