Rhox6 MGI Mouse Gene Detail - MGI:1202888

Symbol

Rhox6
Name

reproductive homeobox 6
Synonyms

Psx1

Feature Type

protein coding gene
IDs

MGI:1202888
NCBI Gene: 19202
Member of

Rhox cluster
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

ChrX:36915932-36918734 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 22.08 cM, cytoband A2-A4
Mapping Data

5 experiments

SNPs within 2kb

17 from dbSNP Build 142
Strain Annotations

13
PCR

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1202888	protein coding gene	ChrX:36915787-36918734 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0035654	protein coding gene	ChrX:32831969-32834994 (-)
A/J	MGP_AJ_G0035640	protein coding gene	ChrX:32908761-32911841 (-)
AKR/J	MGP_AKRJ_G0035556	protein coding gene	ChrX:33557094-33560436 (+)
BALB/cJ	MGP_BALBcJ_G0035623	protein coding gene	ChrX:32589024-32597900 (-)
C3H/HeJ	MGP_C3HHeJ_G0035328	protein coding gene	ChrX:33162606-33165315 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0036153	protein coding gene	ChrX:33539948-33541793 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033005	protein coding gene	ChrX:31202727-31205670 (+)
CAST/EiJ	MGP_CASTEiJ_G0034618	protein coding gene	ChrX:21188507-21191459 (-)
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0035454	protein coding gene	ChrX:32652815-32662113 (+)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	MGP_NODShiLtJ_G0035443	protein coding gene	ChrX:34753649-34756922 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036171	protein coding gene	ChrX:32765408-32771674 (+)
PWK/PhJ	MGP_PWKPhJ_G0034320	protein coding gene	ChrX:20690918-20712570 (+)
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

RHOXF2, Rhox homeobox family member 2

Vertebrate Orthologs

5

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RHOXF2, Rhox homeobox family member 2
Synonyms

CT107, PEPP2, PEPP-2, THG1
Links

HGNC:30011

NCBI Gene ID: 84528

neXtProt AC: NX_Q9BQY4

UniProt: Q9BQY4
Chr Location

Xq24; chrX:120158613-120165630 (+) GRCh38

Human Ortholog

RHOXF2B, Rhox homeobox family member 2B
Links

HGNC:33519

NCBI Gene ID: 727940

neXtProt AC: NX_P0C7M4

UniProt: P0C7M4
Chr Location

Xq24; chrX:120072264-120077690 (-) GRCh38

MGI Vertebrate Homology

Rhox6 stringent orthology
2 human;1 mouse;3 rat
HCOP

vertebrate homology predictions: RHOXF2, RHOXF2B
Gene Tree

Rhox6

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Phenotype Summary

3 phenotype references

All Mutations and Alleles

2
Gene trapped

1
Targeted

1
Genomic Mutations

1 involving Rhox6
Find Mice (IMSR)

1 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

1038
Tissues

230
cDNA Data

22
Literature Summary

18

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

28
RefSeq

2
UniProt

2
CCDS

CCDS30080.1

Ensembl

ENSMUSG00000006200 (Evidence)
NCBI Gene

19202

			Length	Strain/Species	Flank
genomic	19202	NCBI Gene Model \| MGI Sequence Detail	2803	C57BL/6J	± kb
transcript	NM_008955	RefSeq \| MGI Sequence Detail	882	Not Specified
polypeptide	NP_032981	RefSeq \| MGI Sequence Detail	227	Not Specified

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UniProt

2 Sequences
InterPro Domains

IPR001356 Homeobox domain

IPR009057 Homeobox-like domain superfamily

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All nucleic 30

Genomic 1

cDNA 22

Primer pair 6

Other 1

Microarray probesets 3

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MGI:2147982, MGI:2148022

Summaries

All 42

Developmental Gene Expression 18

Gene Ontology 1

Phenotypes 3
Earliest

J:46103 Han YJ, et al., Psx, a novel murine homeobox gene expressed in placenta. Gene. 1998 Jan 30;207(2):159-66
Latest

J:283357 Nowotschin S, et al., The emergent landscape of the mouse gut endoderm at single-cell resolution. Nature. 2019 May;569(7756):361-367

TSS for Rhox6:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr160770	ChrX:36915832-36915839 (+)	-96 bp
Tssr160771	ChrX:36915884-36915887 (+)	-46 bp
Tssr160772	ChrX:36915890-36915896 (+)	-39 bp
Tssr160773	ChrX:36915921-36915924 (+)	-9 bp
Tssr160774	ChrX:36916238-36916302 (+)	338 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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