Tesk1
Gene Detail

Symbol Name ID

Tesk1 testis specific protein kinase 1 MGI:1201675

Feature Type

protein coding gene

Genetic Map

Chromosome 4

23.04 cM, cytoband A5-C1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:43441939-43448064 bp, + strand From VEGA annotation of GRCm38   6126 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:4577  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: dual specificity testis-specific protein kinase
Gene Tree: Tesk1

Human homologs

Human Homolog		TESK1, testis-specific kinase 1
NCBI Gene ID		7016
neXtProt AC		NX_Q15569
Human Chr (Location)		9p13; chr9:35605281-35610038 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	phosphorylation
Function	ATP binding, kinase activity, ...

External Resources: FuncBase

Expression

cDNA source data(7)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) Genomic(4) cDNA(7) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000006821 (Evidence)
Ensembl Gene Model	ENSMUSG00000028458 (Evidence)
Entrez Gene	21754 (Evidence)
NIA Mouse Gene Index	U004232
EC	2.7.12.1
Consensus CDS Project	CCDS18094.1
International Mouse Knockout Project Status	Tesk1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006821	VEGA Gene Model | MGI Sequence Detail	6126	C57BL/6J
transcript	OTTMUST00000015733	VEGA | MGI Sequence Detail	3947	Not Applicable
polypeptide	OTTMUSP00000007229	VEGA | MGI Sequence Detail	627	Not Applicable

All sequences(29) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(32 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017441	Protein kinase, ATP binding site
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR001245	Serine-threonine/tyrosine-protein kinase catalytic domain
InterPro	IPR015782	Testis-specific kinase 1
InterPro	IPR008266	Tyrosine-protein kinase, active site
Protein Ontology	PR:000016241	dual specificity testis-specific protein kinase 1

References

(Earliest) J:46073 Toshima J, et al., Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene. Gene. 1998 Jan 12;206(2):237-45
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)

Other accession IDs

MGI:2140247