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Tesk1 Gene Detail
Summary
  • Symbol
    Tesk1
  • Name
    testis specific protein kinase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201675
    NCBI Gene: 21754
  • Gene Overview
    MyGene.info: TESK1
Location & Maps
more
  • Sequence Map
    Chr4:43441939-43448064 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6126 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 23.04 cM, cytoband A5-C1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TESK1, testis-specific kinase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TESK1, testis-specific kinase 1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 7016
    neXtProt AC: NX_Q15569

  • Chr Location
    9p13; chr9:35605284-35610041 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Chemically and radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Tesk1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006821 VEGA Gene Model | MGI Sequence Detail 6126 C57BL/6J ±  kb
transcript OTTMUST00000015733 VEGA | MGI Sequence Detail 3947 Not Applicable  
polypeptide OTTMUSP00000007229 VEGA | MGI Sequence Detail 627 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    151 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000016241 dual specificity testis-specific protein kinase 1
  • EC
  • InterPro Domains
    IPR015782 Dual specificity testis-specific protein kinase 1
    IPR017441 Protein kinase, ATP binding site
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
    IPR008266 Tyrosine-protein kinase, active site
Molecular
Reagents
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  • All nucleic 12
    Genomic 4
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2140247
References
more
  • Summaries
    All 26
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:46073 Toshima J, et al., Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene. Gene. 1998 Jan 12;206(2):237-45
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory