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Tesk1 Gene Detail
Summary
  • Symbol
    Tesk1
  • Name
    testis specific protein kinase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1201675
    NCBI Gene: 21754
  • Gene Overview
    MyGene.info: TESK1
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:43442277-43448075 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 23.04 cM, cytoband A5-C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1201675
protein coding gene Chr4:43441939-43448075 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028205
protein coding gene Chr4:41553085-41559210 (+)
A/J MGP_AJ_G0028161
protein coding gene Chr4:40080406-40086496 (+)
AKR/J MGP_AKRJ_G0028113
protein coding gene Chr4:40992096-40998244 (+)
BALB/cJ MGP_BALBcJ_G0028181
protein coding gene Chr4:40170112-40176202 (+)
C3H/HeJ MGP_C3HHeJ_G0027903
protein coding gene Chr4:41617199-41623289 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028622
protein coding gene Chr4:43114106-43120231 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025934
protein coding gene Chr4:37531461-37537805 (+)
CAST/EiJ MGP_CASTEiJ_G0027343
protein coding gene Chr4:41121654-41127783 (+)
CBA/J MGP_CBAJ_G0027869
protein coding gene Chr4:44418800-44424918 (+)
DBA/2J MGP_DBA2J_G0028018
protein coding gene Chr4:39992374-39998492 (+)
FVB/NJ MGP_FVBNJ_G0027985
protein coding gene Chr4:39210574-39216692 (+)
LP/J MGP_LPJ_G0028117
protein coding gene Chr4:41609952-41616077 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028009
protein coding gene Chr4:47683388-47689536 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028658
protein coding gene Chr4:41185189-41191314 (+)
PWK/PhJ MGP_PWKPhJ_G0027069
protein coding gene Chr4:40034890-40041012 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026895
protein coding gene Chr4:40751302-40757415 (+)
WSB/EiJ MGP_WSBEiJ_G0027423
protein coding gene Chr4:41089841-41095969 (+)



Homology
more
  • Human Ortholog
    TESK1, testis associated actin remodelling kinase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TESK1, testis associated actin remodelling kinase 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 7016
    neXtProt AC: NX_Q15569
    UniProt: Q15569

  • Chr Location
    9p13.3; chr9:35605284-35610041 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21754 NCBI Gene Model | MGI Sequence Detail 5799 C57BL/6J ±  kb
transcript NM_011571 RefSeq | MGI Sequence Detail 3620 C57BL/6  
polypeptide O70146 UniProt | EBI | MGI Sequence Detail 627 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 4
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140247
References
more
  • Summaries
    All 31
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:46073 Toshima J, et al., Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene. Gene. 1998 Jan 12;206(2):237-45
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory