Sequence Detail

ID/Version

O70146 O70147 Q499W7 (UniProt | EBI)

Last sequence update: 2007-10-23
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Dual specificity testis-specific protein kinase 1; EC=2.7.12.1;AltName: Full=Testicular protein kinase 1;

Provider

SWISS-PROT

Sequence

Polypeptide 627 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tesk1	testis specific protein kinase 1	44	97	4	4

Sequence references in MGI

J:46073 Toshima J, et al., Structural organization and chromosomal localization of the mouse tesk1 (testis-specific protein kinase 1) gene. Gene. 1998 Jan 12;206(2):237-45
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:130605 Chandramouli S, et al., Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling. J Biol Chem. 2008 Jan 18;283(3):1679-91
J:278520 Wang L, et al., Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1). Sci Rep. 2018 Aug 16;8(1):12286
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87