About   Help   FAQ
Fubp1 Gene Detail
Summary
  • Symbol
    Fubp1
  • Name
    far upstream element (FUSE) binding protein 1
  • Synonyms
    9530027K12Rik, FBP, Fubp, Fubp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196294
    NCBI Gene: 51886
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr3:152210422-152236826 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      26405 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 77.05 cM
  • Mapping Data
    7 experiments
Homology
more
  • Human Ortholog
    FUBP1, far upstream element binding protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FUBP1, far upstream element binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP, FUBP, hDH V
  • Links
    NCBI Gene ID: 8880
    neXtProt AC: NX_Q96AE4
    UniProt: Q96AE4

  • Chr Location
    1p31.1; chr1:77944055-77979494 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    33 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit pre- and perinatal lethality, cerebral hyperplasia, pale liver, hypoplastic lungs, spleen, thymus and bone marrow, cardiac hypertrophy, placental distress, small size, and anemia associated with variable, multilineage hematopoietic deficiency.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    97
  • Tissues
    76
  • cDNA Data
    310
  • Literature Summary
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000053719 VEGA Gene Model | MGI Sequence Detail 26405 C57BL/6J ±  kb
    transcript OTTMUST00000133762 VEGA | MGI Sequence Detail 4846 Not Applicable  
    polypeptide OTTMUSP00000071043 VEGA | MGI Sequence Detail 700 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      168 from dbSNP Build 142
    • PCR
      1
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 315
      Genomic 1
      cDNA 310
      Primer pair 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1336165, MGI:1924642
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 12
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:40384 Craig JC, et al., Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
    • Latest
      J:229985 Zhou W, et al., Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels. Am J Pathol. 2016 Mar;186(3):701-15
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.     		last database update
    06/12/2018
    MGI 6.12     		The Jackson Laboratory