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Fubp1 Gene Detail
Summary
  • Symbol
    Fubp1
  • Name
    far upstream element (FUSE) binding protein 1
  • Synonyms
    9530027K12Rik, FBP, Fubp, Fubp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196294
    NCBI Gene: 51886
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:152210422-152236826 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 77.05 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196294
 protein coding gene Chr3:152210422-152236830 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027988
 protein coding gene Chr3:156062902-156089231 (+)
A/J MGP_AJ_G0027947
 protein coding gene Chr3:150403893-150430513 (+)
AKR/J MGP_AKRJ_G0027913
 protein coding gene Chr3:154362112-154388502 (+)
BALB/cJ MGP_BALBcJ_G0027959
 protein coding gene Chr3:150240748-150267162 (+)
C3H/HeJ MGP_C3HHeJ_G0027689
 protein coding gene Chr3:154806535-154832981 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028402
 protein coding gene Chr3:161208450-161235919 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025740
 protein coding gene Chr3:145239440-145266613 (+)
CAST/EiJ MGP_CASTEiJ_G0027142
 protein coding gene Chr3:154882108-154908418 (+)
CBA/J MGP_CBAJ_G0027664
 protein coding gene Chr3:166992371-167018681 (+)
DBA/2J MGP_DBA2J_G0027804
 protein coding gene Chr3:149509818-149536235 (+)
FVB/NJ MGP_FVBNJ_G0027771
 protein coding gene Chr3:146886766-146913129 (+)
LP/J MGP_LPJ_G0027915
 protein coding gene Chr3:157438803-157465087 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027804
 protein coding gene Chr3:175522995-175550611 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028461
 protein coding gene Chr3:154056887-154083289 (+)
PWK/PhJ MGP_PWKPhJ_G0026865
 protein coding gene Chr3:149395291-149422118 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026693
 protein coding gene Chr3:152216442-152242642 (+)
WSB/EiJ MGP_WSBEiJ_G0027222
 protein coding gene Chr3:155065872-155092406 (+)



Homology
more
  • Human Ortholog
    FUBP1, far upstream element binding protein 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FUBP1, far upstream element binding protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP, FUBP, hDH V
  • Links
    NCBI Gene ID: 8880
    neXtProt AC: NX_Q96AE4
    UniProt: Q96AE4

  • Chr Location
    1p31.1; chr1:77944055-77979494 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    37 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit pre- and perinatal lethality, cerebral hyperplasia, pale liver, hypoplastic lungs, spleen, thymus and bone marrow, cardiac hypertrophy, placental distress, small size, and anemia associated with variable, multilineage hematopoietic deficiency.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    76
  • cDNA Data
    312
  • Literature Summary
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028034 Ensembl Gene Model | MGI Sequence Detail 26405 C57BL/6J ±  kb
    transcript ENSMUST00000199876 Ensembl | MGI Sequence Detail 4846 Not Applicable  
    polypeptide ENSMUSP00000143618 Ensembl | MGI Sequence Detail 700 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 317
      Genomic 1
      cDNA 312
      Primer pair 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1336165, MGI:1924642
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 12
      Gene Ontology 9
      Phenotypes 12
    • Earliest
      J:40384 Craig JC, et al., Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
    • Latest
      J:229985 Zhou W, et al., Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels. Am J Pathol. 2016 Mar;186(3):701-15
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    02/23/2021
    MGI 6.16     		The Jackson Laboratory