Ctnnd2
Gene Detail

Symbol Name ID

Ctnnd2 catenin (cadherin associated protein), delta 2 MGI:1195966

Synonyms

Catnd2, neurojugin, Nprap

Feature Type

protein coding gene

Genetic Map

Chromosome 15

12.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr15:30172593-31029311 bp, + strand From Ensembl annotation of GRCm38   856719 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55574  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ctnnd2

Human homologs

Human Homolog		CTNND2, catenin (cadherin-associated protein), delta 2
NCBI Gene ID		1501
neXtProt AC		NX_Q9UQB3
Human Synonyms		GT24, NPRAP
Human Chr (Location)		5p15.2; chr5:10971952-11904110 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CTNND2

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Mice homozygous for a reporter allele exhibit abnormal conditioning, spatial learning and coordination behaviors and abnormal long term potentiation.

 

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	cell adhesion, learning, ...
Component	cell junction, neuron projection, ...

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (51)    Tissues (27)    Images (14)
Theiler Stages: 23, 24, 28

Assay Type	Results
Immunohistochemistry	3
RNA in situ	30
Northern blot	9
Western blot	9

cDNA source data(76)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(77) cDNA(76) Primer pair(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000022240 (Evidence)
Entrez Gene	18163 (Evidence)
UniGene	321648
DFCI	TC1580500, TC1613461, TC1656566
DoTS	DT.101263848, DT.110819819, DT.40145414, DT.55278288, DT.91310054, DT.94197102
NIA Mouse Gene Index	U036058
Consensus CDS Project	CCDS27405.1
International Mouse Knockout Project Status	Ctnnd2

Sequences

Length	Strain/Species
genomic	ENSMUSG00000022240	Ensembl Gene Model | MGI Sequence Detail	856719	C57BL/6J
transcript	ENSMUST00000081728	Ensembl | MGI Sequence Detail	5914	Not Applicable
polypeptide	ENSMUSP00000080427	Ensembl | MGI Sequence Detail	1246	Not Applicable

All sequences(40) RefSeq(2) UniProt(8)

Polymorphisms

SNPs within 2kb(10408 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR000225	Armadillo
InterPro	IPR011989	Armadillo-like helical
InterPro	IPR016024	Armadillo-type fold
Protein Ontology	PR:000006013	catenin delta-2

References

(Earliest) J:43456 Paffenholz R, et al., Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family. Differentiation. 1997 Aug;61(5):293-304
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)