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Ctnnd2
Gene Detail
Symbol

Name
ID
Ctnnd2
catenin (cadherin associated protein), delta 2
MGI:1195966
Synonyms
Catnd2, neurojugin, Nprap
Feature Type
protein coding gene
Genetic Map
Chromosome 15
12.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:30172593-31029311 bp, + strand
From Ensembl annotation of GRCm38

  856719 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55574  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: CTNND2
Gene Tree: Ctnnd2

Human
homologs
CTNND2, catenin (cadherin-associated protein), delta 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 1501
neXtProt AC: NX_Q9UQB3

Human Synonyms: GT24, NPRAP

Human Chr (Location): 5p15.2; chr5:10971840-11904043 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a reporter allele exhibit abnormal conditioning, spatial learning and coordination behaviors and abnormal long term potentiation.
 
Interactions
Ctnnd2 interacts with 310 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process cell adhesion, dendritic spine morphogenesis, ...
Component cell junction, cell projection, ...
Function beta-catenin binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (83)    Tissues (41)    Images (32)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 19
RNA in situ 46
Northern blot 9
Western blot 9
cDNA source data(76)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ctnnd2 ; ZFIN ctnnd2a, ctnnd2b    NEW 
Molecular
reagents
All nucleic(78) cDNA(77) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000022240 (Evidence)
Entrez Gene 18163 (Evidence)
UniGene 321648
DFCI TC1580500, TC1613461, TC1656566
DoTS DT.94197102, DT.91310054, DT.55278288, DT.40145414, DT.110819819, DT.101263848
NIA Mouse Gene Index U036058
Consensus CDS Project CCDS27405.1
International Mouse Phenotyping Consortium Status Ctnnd2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022240 Ensembl Gene Model | MGI Sequence Detail 856719 C57BL/6J ±  kb
transcript ENSMUST00000081728 Ensembl | MGI Sequence Detail 5914 Not Applicable 
polypeptide ENSMUSP00000080427 Ensembl | MGI Sequence Detail 1246 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(6) UniProt(8)
Polymorphisms
SNPs within 2kb(10408 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000225 Armadillo
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
Protein Ontology PR:000006013 catenin delta-2
References
(Earliest) J:43456 Paffenholz R, et al., Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family. Differentiation. 1997 Aug;61(5):293-304
(Latest) J:221282 Nopparat J, et al., delta-Catenin, a Wnt/beta-catenin modulator, reveals inducible mutagenesis promoting cancer cell survival adaptation and metabolic reprogramming. Oncogene. 2015 Mar 19;34(12):1542-52
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory