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Per2
Gene Detail
Symbol

Name
ID
Per2
period circadian clock 2
MGI:1195265
Synonyms
mKIAA0347, mPer2
Feature Type
protein coding gene
Genetic Map
Chromosome 1
46.13 cM, cytoband C5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:91415982-91459324 bp, - strand
From VEGA annotation of GRCm38

  43343 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7885  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Per2

Human
homologs
Human Homolog PER2, period circadian clock 2
NCBI Gene ID 8864
neXtProt AC  NX_O15055
Human Synonyms  FASPS, FASPS1
Human Chr (Location)  2q37.3; chr2:238244038-238290102 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PER2
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Targeted(9)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mutants have a partially functional circadian clock, exhibiting a short circadian period followed by loss of circadian rhythmicity in constant darkness. Mutants are also deficient in DNA damage responses and show increased sensitivity to gamma radiation and tumor development.
 
Interactions
Per2 interacts with 288 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (16 records)
Data Summary: Results (382)    Tissues (199)    Images (77)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 7
RNA in situ 364
RT-PCR 11
cDNA source data(13)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(13) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000048493 (Evidence)
Ensembl Gene ModelENSMUSG00000055866 (Evidence)
Entrez Gene18627 (Evidence)
DFCITC1579956, TC1606867
DoTSDT.60101432, DT.91369157
Consensus CDS ProjectCCDS35663.1
International Mouse Knockout Project StatusPer2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048493 VEGA Gene Model | MGI Sequence Detail 43343 C57BL/6J ±  kb
transcript OTTMUST00000124300 VEGA | MGI Sequence Detail 5833 Not Applicable 
polypeptide OTTMUSP00000067668 VEGA | MGI Sequence Detail 1257 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(6)
Polymorphisms
SNPs within 2kb(409 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012548 period circadian protein homolog 2
References
(Earliest) J:44820 Albrecht U, et al., A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell. 1997 Dec 26;91(7):1055-64
(Latest) J:211807 Bedont JL, et al., Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus. Cell Rep. 2014 May 8;7(3):609-22
All references(212)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory