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Per2
Gene Detail
 Symbol
Name
ID
Per2
period circadian clock 2
MGI:1195265
Synonyms mKIAA0347, mPer2
Feature Type protein coding gene
Genetic Map
Chromosome 1
46.13 cM, cytoband C5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:91415982-91459328 bp, - strand
From NCBI annotation of GRCm38

  43347 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7885  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Per2

Human
homologs
Human Homolog PER2, period circadian clock 2
NCBI Gene ID 8864
neXtProt AC  NX_O15055
Human Synonyms  FASPS, FASPS1
Human Chr (Location)  2q37.3; chr2:238244038-238290102 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PER2
Alleles
and
phenotypes
All alleles(9) : Targeted(9)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mutants have a partially functional circadian clock, exhibiting a short circadian period followed by loss of circadian rhythmicity in constant darkness. Mutants are also deficient in DNA damage responses and show increased sensitivity to gamma radiation and tumor development.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process circadian rhythm, negative regulation of transcription, DNA-templated, ...
Component cytoplasm, nucleus
Function protein binding, transcription factor binding transcription factor activity
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (382)    Tissues (189)    Images (77)
Theiler Stages: 17, 19, 21, 22, 23, 25, 28
Assay TypeResults
Immunohistochemistry 7
RNA in situ 364
RT-PCR 11
cDNA source data(13)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(16) cDNA(13) Primer pair(2) Other(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000055866 (Evidence)
Entrez Gene18627 (Evidence)
DFCITC1579956, TC1606867
DoTSDT.60101432, DT.91369157
Consensus CDS ProjectCCDS35663.1
International Mouse Knockout Project StatusPer2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 18627 NCBI Gene Model | MGI Sequence Detail 43347 C57BL/6J ±  kb
transcript NM_011066 RefSeq | MGI Sequence Detail 5845 C57BL/6 
polypeptide NP_035196 RefSeq | MGI Sequence Detail 1257 C57BL/6 

For the selected sequences
All sequences(25) RefSeq(6)
Polymorphisms SNPs within 2kb(409 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000012548 period circadian protein homolog 2
References (Earliest) J:44820 Albrecht U, et al., A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell. 1997 Dec 26;91(7):1055-64
(Latest) J:210648 Adamovich Y, et al., Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. Cell Metab. 2014 Feb 4;19(2):319-30
All references(209)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory