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Tgif1
Gene Detail
 Symbol
Name
ID
Tgif1
TGFB-induced factor homeobox 1
MGI:1194497
Synonyms Tgif
Feature Type protein coding gene
Genetic Map
Chromosome 17
41.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:70844205-70853546 bp, - strand
From VEGA annotation of GRCm38

  9342 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7574  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tgif1

Human
homologs
Human Homolog TGIF1, TGFB-induced factor homeobox 1
NCBI Gene ID 7050
neXtProt AC  NX_Q15583
Human Synonyms  HPE4, TGIF
Human Chr (Location)  18p11.3; chr18:3411927-3458411 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TGIF1
Alleles
and
phenotypes
All alleles(118) : Targeted(9) Gene trapped(109)
 
Homozygous null mice display normal growth, behavior and fertility.
 
Human Diseases Modeled Using Mouse Tgif1 (1)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process determination of left/right symmetry, dorsal/ventral pattern formation, ...
Component nucleus
Function chromatin binding, co-SMAD binding, ...
External Resources: FuncBase
Expression
Literature Summary: (20 records)
Data Summary: Results (247)    Tissues (128)    Images (38)
Theiler Stages: 2, 3, 4, 5, 8, 10, 11, 12, 13, 15, 16, 17, 21, 22, 23, 26, 27, 28
Assay TypeResults
RNA in situ 144
RT-PCR 103
cDNA source data(173)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(176) cDNA(173) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031400 (Evidence)
Ensembl Gene ModelENSMUSG00000047407 (Evidence)
Entrez Gene21815 (Evidence)
UniGene101034
DFCITC1574986, TC1593722, TC1637895, TC1703875
DoTSDT.101147484, DT.101201822, DT.493828, DT.97414571
NIA Mouse Gene IndexU038033
Consensus CDS ProjectCCDS37683.1, CCDS50174.1, CCDS50175.1
International Mouse Knockout Project StatusTgif1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031400 VEGA Gene Model | MGI Sequence Detail 9342 C57BL/6J ±  kb
transcript OTTMUST00000078088 VEGA | MGI Sequence Detail 1714 Not Applicable 
polypeptide OTTMUSP00000041459 VEGA | MGI Sequence Detail 305 Not Applicable 

For the selected sequences
All sequences(81) RefSeq(14) UniProt(7)
Polymorphisms SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008422 Homeobox KN domain
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
Protein Ontology PR:000016288 homeobox protein TGIF1
References (Earliest) J:32973 Bertolino E, et al., Expression of a novel murine homeobox gene in the developing cerebellar external granular layer during its proliferation. Dev Dyn. 1996 Apr;205(4):410-20
(Latest) J:206081 Yan L, et al., Tgif1 regulates quiescence and self-renewal of hematopoietic stem cells. Mol Cell Biol. 2013 Dec;33(24):4824-33
All references(71)
Other
accession IDs
MGI:2146782, MGI:2146872

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory