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H3f3b
Gene Detail
Symbol

Name
ID
H3f3b
H3 histone, family 3B
MGI:1101768
Synonyms
9430068D06Rik, H3.3B
Feature Type
protein coding gene
Genetic Map
Chromosome 11
80.91 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:116021912-116027962 bp, - strand
From VEGA annotation of GRCm38

  6051 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134170  Vertebrate Homology Class
2 human; 2 mouse; 2 rat; 3 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 2 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: histone H3
Gene Tree: H3f3b

Human
homologs
Human Homolog H3F3A, H3 histone, family 3A
NCBI Gene ID 3020
neXtProt AC  NX_P84243
Human Synonyms  H3.3A, H3F3
Human Chr (Location)  1q42.12; chr1:226062707-226072002 (+)  GRCh38
Human Homolog H3F3B, H3 histone, family 3B (H3.3B)
NCBI Gene ID 3021
neXtProt AC  NX_P84243
Human Synonyms  H3.3B
Human Chr (Location)  17q25.1; chr17:75776434-75779779 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(11) Targeted(5)
Incidental mutations (data from APF )
 
Mice heterozygous for a reporter allele exhibit reduced body size and male infertility due to failure of spermiogenesis.
 
Interactions
H3f3b interacts with 291 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (19)    Tissues (13)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
RT-PCR 7
cDNA source data(58)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(60) cDNA(59) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000003689 (Evidence)
Ensembl Gene ModelENSMUSG00000016559 (Evidence)
Entrez Gene15081 (Evidence)
DFCITC1573650, TC1669515, TC1599687, TC1589656
DoTSDT.99871185, DT.91554613, DT.101718372, DT.97391691, DT.101283672, DT.102540018, DT.101220866
NIA Mouse Gene IndexU040577, U063021, U033638
Consensus CDS ProjectCCDS36377.1
International Mouse Knockout Project StatusH3f3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003689 VEGA Gene Model | MGI Sequence Detail 6051 C57BL/6J ±  kb
transcript OTTMUST00000007997 VEGA | MGI Sequence Detail 2514 Not Applicable 
polypeptide OTTMUSP00000003888 VEGA | MGI Sequence Detail 136 Not Applicable 

For the selected sequences
All sequences(90) RefSeq(4)
Polymorphisms
SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000008425 histone H3.3
References
(Earliest) J:42392 Hraba-Renevey S, et al., Expression of a mouse replacement histone H3.3 gene with a highly conserved 3' noncoding region during SV40- and polyoma-induced Go to S-phase transition. Nucleic Acids Res. 1989 Apr 11;17(7):2449-61
(Latest) J:214808 Yuen BT, et al., Histone H3.3 regulates dynamic chromatin states during spermatogenesis. Development. 2014 Sep;141(18):3483-94
All references(41)
Other
accession IDs
MGI:1926214

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory