H3f3b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H3f3b
H3.3 histone B
MGI:1101768

15 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
H3f3b^{tm1.1(KOMP)Mbp}/H3f3b^{tm1.1(KOMP)Mbp} C57BL/6N-H3f3b^{tm1.1(KOMP)Mbp}/Tcp	abnormal kidney morphology	J:211773
	increased circulating cholesterol level	J:211773
	increased startle reflex	J:211773
	polycystic kidney	J:211773
H3f3b^tm1.1Mnn/H3f3b^tm1.1Mnn involves: 129S1/SvImJ * 129S4/SvJaeSor	no abnormal phenotype detected	J:194069
H3f3b^tm1.1Psk/H3f3b⁺ involves: C57BL/6N * FVB/N	lethality, incomplete penetrance	J:194593
H3f3b^tm1.1Psk/H3f3b^tm1.1Psk involves: C57BL/6N * FVB/N	abnormal cell cycle	J:194593
	abnormal cell nucleus morphology	J:194593
	abnormal chromosome morphology	J:194593
	embryonic growth retardation	J:194593
	lethality, incomplete penetrance	J:194593
	male infertility	J:194593
	polyploidy	J:194593
	reduced female fertility	J:194593
H3f3b^tm1.2Mnn/H3f3b⁺ involves: 129S1/Sv * 129S1/SvImJ * 129S4/SvJaeSor	arrest of spermiogenesis	J:194069
	decreased body size	J:194069
	male infertility	J:194069
H3f3b^tm1Psk/H3f3b^tm1Psk involves: C57BL/6N	no abnormal phenotype detected	J:194593

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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