Fmo3
Gene Detail

Symbol Name ID

Fmo3 flavin containing monooxygenase 3 MGI:1100496

Feature Type

protein coding gene

Genetic Map

Chromosome 1

70.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:162953802-162984528 bp, - strand From VEGA annotation of GRCm38   30727 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128199  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: dimethylaniline monooxygenase (N-oxide-forming)
Gene Tree: Fmo3

Human homologs

Human Homolog		FMO3, flavin containing monooxygenase 3
NCBI Gene ID		2328
neXtProt AC		NX_P31513
Human Synonyms		dJ127D3.1, FMOII, TMAU
Human Chr (Location)		1q24.3; chr1:171060018-171086959 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human FMO3

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	drug metabolic process
Component	endoplasmic reticulum, integral to membrane, ...
Function	amino acid binding, flavin adenine dinucleotide binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (123)    Tissues (123)    Images (8)
Theiler Stages: 19, 22, 23, 28

Assay Type	Results
RNA in situ	123

cDNA source data(20)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) cDNA(20) Primer pair(1) Other(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000024141 (Evidence)
Ensembl Gene Model	ENSMUSG00000026691 (Evidence)
Entrez Gene	14262 (Evidence)
UniGene	2900
DFCI	TC1585511, TC1596699
DoTS	DT.490637, DT.94149774
NIA Mouse Gene Index	U021975
EC	1.14.13.148, 1.14.13.8
Consensus CDS Project	CCDS15426.1
International Mouse Knockout Project Status	Fmo3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000024141	VEGA Gene Model | MGI Sequence Detail	30727	C57BL/6J
transcript	OTTMUST00000059064	VEGA | MGI Sequence Detail	2044	Not Applicable
polypeptide	OTTMUSP00000028696	VEGA | MGI Sequence Detail	534	Not Applicable

All sequences(25) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(150 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR012143	Dimethylaniline monooxygenase, N-oxide-forming
InterPro	IPR000960	Flavin monooxygenase FMO
InterPro	IPR002255	Flavin monooxygenase (FMO) 3
InterPro	IPR020946	Flavin monooxygenase-like
Protein Ontology	PR:000007576	dimethylaniline monooxygenase [N-oxide-forming] 3

References

(Earliest) J:16633 Lawton MP, et al., A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch Biochem Biophys. 1994 Jan;308(1):254-7
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)

Other accession IDs

MGI:2138561