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Fmo3 Gene Detail
Summary
  • Symbol
    Fmo3
  • Name
    flavin containing monooxygenase 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1100496
    NCBI Gene: 14262
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162953800-162984528 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 70.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    284 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1100496
protein coding gene Chr1:162953799-162984528 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016668
protein coding gene Chr1:168330831-168361421 (-)
A/J MGP_AJ_G0016649
protein coding gene Chr1:161463130-161496628 (-)
AKR/J MGP_AKRJ_G0016615
protein coding gene Chr1:166359396-166396340 (-)
BALB/cJ MGP_BALBcJ_G0016610
protein coding gene Chr1:161974098-162003345 (-)
C3H/HeJ MGP_C3HHeJ_G0016434
protein coding gene Chr1:166552696-166582904 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017071
protein coding gene Chr1:173970827-174004297 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014780
protein coding gene Chr1:153492227-153516354 (-)
CAST/EiJ MGP_CASTEiJ_G0016014
protein coding gene Chr1:166210541-166240874 (-)
CBA/J MGP_CBAJ_G0016409
protein coding gene Chr1:180185839-180217834 (-)
DBA/2J MGP_DBA2J_G0016515
protein coding gene Chr1:160390877-160426402 (-)
FVB/NJ MGP_FVBNJ_G0016513
protein coding gene Chr1:158821216-158853374 (-)
LP/J MGP_LPJ_G0016586
protein coding gene Chr1:169420047-169453361 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016538
protein coding gene Chr1:187675654-187711106 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017107
protein coding gene Chr1:166181287-166217516 (-)
PWK/PhJ MGP_PWKPhJ_G0015800
protein coding gene Chr1:159581716-159610494 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015587
protein coding gene Chr1:165072951-165104725 (-)
WSB/EiJ MGP_WSBEiJ_G0016076
protein coding gene Chr1:166362243-166386159 (-)



Homology
more
  • Human Ortholog
    FMO3, flavin containing monooxygenase 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    FMO3, flavin containing monooxygenase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ127D3.1, FMOII, TMAU
  • Links
    NCBI Gene ID: 2328
    neXtProt AC: NX_P31513
    UniProt: P31513

  • Chr Location
    1q24.3; chr1:171090873-171117819 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026691 Ensembl Gene Model | MGI Sequence Detail 30729 C57BL/6J ±  kb
transcript ENSMUST00000028010 Ensembl | MGI Sequence Detail 2046 Not Applicable  
polypeptide ENSMUSP00000028010 Ensembl | MGI Sequence Detail 534 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 21
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138561
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:16633 Lawton MP, et al., A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities. Arch Biochem Biophys. 1994 Jan;308(1):254-7
  • Latest
    J:254352 Schugar RC, et al., The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Rep. 2017 Jun 20;19(12):2451-2461

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory