About   Help   FAQ
Stag1 Gene Detail
Summary
  • Symbol
    Stag1
  • Name
    stromal antigen 1
  • Synonyms
    SA-1, Scc3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098658
    NCBI Gene: 20842
  • Gene Overview
    MyGene.info: STAG1
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:100597709-100958544 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 52.77 cM, cytoband F1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2747 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098658
protein coding gene Chr9:100597709-100959375 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035179
protein coding gene Chr9:102042276-102424196 (+)
A/J MGP_AJ_G0035160
protein coding gene Chr9:98439858-98801336 (+)
AKR/J MGP_AKRJ_G0035092
protein coding gene Chr9:100841893-101211872 (+)
BALB/cJ MGP_BALBcJ_G0035153
protein coding gene Chr9:98119066-98486578 (+)
C3H/HeJ MGP_C3HHeJ_G0034863
protein coding gene Chr9:101262518-101638614 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035673
protein coding gene Chr9:104957884-105353546 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032572
protein coding gene Chr9:96083338-96444701 (+)
CAST/EiJ MGP_CASTEiJ_G0034174
protein coding gene Chr9:101053924-101439207 (+)
CBA/J MGP_CBAJ_G0034831
protein coding gene Chr9:108596361-109016617 (+)
DBA/2J MGP_DBA2J_G0034993
protein coding gene Chr9:97920726-98286296 (+)
FVB/NJ MGP_FVBNJ_G0034941
protein coding gene Chr9:96733839-97093218 (+)
LP/J MGP_LPJ_G0035069
protein coding gene Chr9:102267753-102649527 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034980
protein coding gene Chr9:110474707-110902309 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035695
protein coding gene Chr9:101102465-101472410 (+)
PWK/PhJ MGP_PWKPhJ_G0033881
protein coding gene Chr9:98149633-98526605 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033717
protein coding gene Chr9:101149563-101522134 (+)
WSB/EiJ MGP_WSBEiJ_G0034294
protein coding gene Chr9:100958345-101343211 (+)



Homology
more
  • Human Ortholog
    STAG1, stromal antigen 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STAG1, stromal antigen 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRD47, SA1, SCC3A
  • Links
    NCBI Gene ID: 10274
    neXtProt AC: NX_Q8WVM7
    UniProt: Q8WVM7

  • Chr Location
    3q22.3; chr3:136336235-136752412 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human STAG1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mouse embryos homozygous for a null mutation show developmental delay and die before birth. Heterozygous animals have shorter lifespan and earlier onset of tumourigenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20842 NCBI Gene Model | MGI Sequence Detail 360836 C57BL/6J ±  kb
    transcript NM_001357265 RefSeq | MGI Sequence Detail 6258 C57BL/6  
    polypeptide Q9D3E6 UniProt | EBI | MGI Sequence Detail 1258 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 182
      cDNA 181
      Primer pair 1

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:2143240
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 7
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:42879 Carramolino L, et al., SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs. Gene. 1997 Aug 22;195(2):151-9
    • Latest
      J:231644 Cuadrado A, et al., The contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues. Nucleic Acids Res. 2015 Mar 31;43(6):3056-67

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory