Stag1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stag1
STAG1 cohesin complex component
MGI:1098658

47 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stag1^em1(IMPC)Mbp/Stag1⁺ C57BL/6N-Stag1^em1(IMPC)Mbp/MbpMmucd	abnormal kidney morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	abnormal spleen morphology	J:211773
	blind uterus	J:211773
	enlarged lymph nodes	J:211773
	enlarged seminal vesicle	J:211773
	enlarged spleen	J:211773
	increased circulating triglyceride level	J:211773
	microphthalmia	J:211773
	small kidney	J:211773
	small spleen	J:211773
	urinary bladder obstruction	J:211773
Stag1^em1(IMPC)Mbp/Stag1^em1(IMPC)Mbp C57BL/6N-Stag1^em1(IMPC)Mbp/MbpMmucd	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
Stag1^{Gt(P099A04)Wrst}/Stag1⁺ involves: 129S2/SvPas	abnormal mitosis	J:184720
	abnormal telomere morphology	J:184720
	decreased cell proliferation	J:184720
	decreased incidence of tumors by chemical induction	J:184720
	decreased tumor growth/size	J:184720
	increased carcinoma incidence	J:184720
	increased hepatocellular carcinoma incidence	J:184720
	increased histiocytic sarcoma incidence	J:184720
	increased lymphoma incidence	J:184720
	increased papilloma incidence	J:184720
	increased tumor incidence	J:184720
	kyphosis	J:184720
	premature aging	J:184720
	premature death	J:184720
Stag1^{Gt(P099A04)Wrst}/Stag1^{Gt(P099A04)Wrst} involves: 129S2/SvPas	abnormal bone mineralization	J:184719
	abnormal definitive hematopoiesis	J:184719
	abnormal kidney collecting duct morphology	J:184719
	abnormal mitosis	J:184720
	abnormal muscle morphology	J:184719
	abnormal renal glomerulus morphology	J:184719
	abnormal telomere morphology	J:184720
	abnormal tooth development	J:184719
	aneuploidy	J:184720
	decreased brown adipose tissue amount	J:184719
	decreased cell proliferation	J:184720
	decreased fetal size	J:184719, J:184720
	decreased fibroblast proliferation	J:184720
	decreased hair follicle number	J:184719
	decreased total body fat amount	J:184719
	delayed intramembranous bone ossification	J:184719
	embryonic lethality during organogenesis, incomplete penetrance	J:184720
	lethality throughout fetal growth and development, complete penetrance	J:184720
	thin skin	J:184719

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