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Ifnab Gene Detail
Summary
  • Symbol
    Ifnab
  • Name
    interferon alpha B
  • Feature Type
    protein coding gene
  • IDs
    MGI:1097683
    NCBI Gene: 15974
  • Member of
    Ifna cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr4:88608836-88609505 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 42.02 cM, cytoband C4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1097683
protein coding gene Chr4:88608539-88609596 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028431
protein coding gene Chr4:88554433-88555490 (-)
A/J MGP_AJ_G0028391
protein coding gene Chr4:85473012-85474994 (-)
AKR/J MGP_AKRJ_G0028339
protein coding gene Chr4:87577675-87578732 (-)
BALB/cJ MGP_BALBcJ_G0028410
protein coding gene Chr4:85686854-85687911 (-)
C3H/HeJ MGP_C3HHeJ_G0028123
protein coding gene Chr4:88307502-88308559 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028848
protein coding gene Chr4:91964864-91966028 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026148
protein coding gene Chr4:81454494-81455549 (-)
CAST/EiJ MGP_CASTEiJ_G0027568
protein coding gene Chr4:86293322-86295219 (+)
CBA/J MGP_CBAJ_G0028094
protein coding gene Chr4:94776381-94778143 (-)
DBA/2J MGP_DBA2J_G0028244
protein coding gene Chr4:85250144-85252085 (-)
FVB/NJ MGP_FVBNJ_G0028209
protein coding gene Chr4:84182877-84185417 (-)
LP/J MGP_LPJ_G0028344
protein coding gene Chr4:88911957-88913014 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028239
protein coding gene Chr4:99781067-99783224 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028886
protein coding gene Chr4:87734811-87736965 (-)
PWK/PhJ MGP_PWKPhJ_G0027289
protein coding gene Chr4:83552981-83554064 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027111
protein coding gene Chr4:85262428-85263734 (-)
WSB/EiJ MGP_WSBEiJ_G0027643
protein coding gene Chr4:87933728-87935484 (-)



Homology
more
  • Human Ortholog
    IFNA1, interferon alpha 1
  • Vertebrate Orthologs
    15
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFNA1, interferon alpha 1
  • Synonyms
    IFL, IFN, IFNA@, IFNA13, IFN-ALPHA, IFN-alphaD, leIF D
  • Links
    NCBI Gene ID: 3439
    neXtProt AC: NX_P01562
    UniProt: P01562

  • Chr Location
    9p21.3; chr9:21440454-21441316 (+)  GRCh38.p7

  • Human Ortholog
    IFNA10, interferon alpha 10
  • Synonyms
    IFN-alphaC
  • Links
    NCBI Gene ID: 3446
    neXtProt AC: NX_P01566
    UniProt: P01566

  • Chr Location
    9p21.3; chr9:21206181-21207143 (-)  GRCh38.p7

  • Human Ortholog
    IFNA14, interferon alpha 14
  • Synonyms
    IFN-alphaH, LEIF2H
  • Links
    NCBI Gene ID: 3448
    neXtProt AC: NX_P01570
    UniProt: P01570

  • Chr Location
    9p21.3; chr9:21239202-21239979 (-)  GRCh38.p7

  • Human Ortholog
    IFNA16, interferon alpha 16
  • Synonyms
    IFN-alpha-16, IFN-alphaO
  • Links
    NCBI Gene ID: 3449
    neXtProt AC: NX_P05015
    UniProt: P05015

  • Chr Location
    9p21.3; chr9:21216373-21217311 (-)  GRCh38.p7

  • Human Ortholog
    IFNA17, interferon alpha 17
  • Synonyms
    IFNA, IFN-alphaI, INFA, LEIF2C1
  • Links
    NCBI Gene ID: 3451
    neXtProt AC: NX_P01571
    UniProt: P01571

  • Chr Location
    9p21.3; chr9:21227243-21228222 (-)  GRCh38.p7

  • Human Ortholog
    IFNA2, interferon alpha 2
  • Synonyms
    IFNA, IFNA2B, IFN-alpha-2, IFN-alphaA, leIF A
  • Links
    NCBI Gene ID: 3440
    neXtProt AC: NX_P01563
    UniProt: P01563

  • Chr Location
    9p21.3; chr9:21384255-21385397 (-)  GRCh38.p7

  • Human Ortholog
    IFNA21, interferon alpha 21
  • Synonyms
    IFN-alphaI, leIF-F, LeIF F
  • Links
    NCBI Gene ID: 3452
    neXtProt AC: NX_P01568
    UniProt: P01568

  • Chr Location
    9p21.3; chr9:21165637-21166660 (-)  GRCh38.p7

  • Human Ortholog
    IFNA4, interferon alpha 4
  • Synonyms
    IFN-alpha4a, INFA4
  • Links
    NCBI Gene ID: 3441
    neXtProt AC: NX_P05014
    UniProt: P05014

  • Chr Location
    9p21.3; chr9:21186618-21187599 (-)  GRCh38.p7

  • Human Ortholog
    IFNA5, interferon alpha 5
  • Synonyms
    IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF G
  • Links
    NCBI Gene ID: 3442
    neXtProt AC: NX_P01569
    UniProt: P01569

  • Chr Location
    9p21.3; chr9:21304614-21305313 (-)  GRCh38.p7

  • Human Ortholog
    IFNA6, interferon alpha 6
  • Synonyms
    IFN-alphaK
  • Links
    NCBI Gene ID: 3443
    neXtProt AC: NX_P05013
    UniProt: P05013

  • Chr Location
    9p21.3; chr9:21350318-21350887 (-)  GRCh38.p7

  • Human Ortholog
    IFNA7, interferon alpha 7
  • Synonyms
    IFNA-J, IFN-alphaJ
  • Links
    NCBI Gene ID: 3444
    neXtProt AC: NX_P01567
    UniProt: P01567

  • Chr Location
    9p21.3; chr9:21201469-21202205 (-)  GRCh38.p7

  • Human Ortholog
    IFNA8, interferon alpha 8
  • Synonyms
    IFN-alphaB
  • Links
    NCBI Gene ID: 3445
    neXtProt AC: NX_P32881
    UniProt: P32881

  • Chr Location
    9p21.3; chr9:21409147-21410185 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15974 NCBI Gene Model | MGI Sequence Detail 670 C57BL/6J ±  kb
transcript NM_008336 RefSeq | MGI Sequence Detail 670 Not Specified  
polypeptide NP_032362 RefSeq | MGI Sequence Detail 190 Not Specified  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR000471 Interferon alpha/beta/delta
Molecular
Reagents
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  • All nucleic 3
    Genomic 1
    cDNA 2

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:17550 Daugherty B, et al., Isolation and bacterial expression of a murine alpha leukocyte interferon gene. J Interferon Res. 1984 Fall;4(4):635-43
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory