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Ganab
Gene Detail
 Symbol
Name
ID
Ganab
alpha glucosidase 2 alpha neutral subunit
MGI:1097667
Synonyms G2an, GluII, mKIAA0088
Feature Type protein coding gene
Genetic Map
Chromosome 19
5.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:8898111-8916666 bp, + strand
From NCBI annotation of GRCm38

  18556 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5426  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: lysosomal alpha-glucosidase
Gene Tree: Ganab

Human
homologs
Human Homolog GANAB, glucosidase, alpha; neutral AB
NCBI Gene ID 23193
neXtProt AC  NX_Q14697
Human Synonyms  G2AN, GLUII
Human Chr (Location)  11q12.3; chr11:62624826-62646726 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(24)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ganab interacts with 163 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process carbohydrate metabolic process, metabolic process, ...
Component endoplasmic reticulum, extracellular vesicular exosome, ...
Function carbohydrate binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (187)    Tissues (94)    Images (27)
Theiler Stages: 22
Assay TypeResults
RNA in situ 187
cDNA source data(408)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(409) cDNA(408) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000071650 (Evidence)
Entrez Gene14376 (Evidence)
UniGene3196
DFCITC1574004, TC1586987, TC1603245, TC1605829, TC1614925, TC1778777
DoTSDT.101148093, DT.101390641, DT.102558068, DT.94241778, DT.94411986, DT.94412028, DT.94412045
NIA Mouse Gene IndexU019133
EC3.2.1.84
Consensus CDS ProjectCCDS29557.1
International Mouse Knockout Project StatusGanab
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 14376 NCBI Gene Model | MGI Sequence Detail 18556 C57BL/6J ±  kb
transcript NM_008060 RefSeq | MGI Sequence Detail 3974 C57BL/6 
polypeptide Q8BHN3 UniProt | EBI | MGI Sequence Detail 944 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011013 Galactose mutarotase-like domain
InterPro IPR000322 Glycoside hydrolase, family 31
InterPro IPR025887 Glycoside hydrolase family 31, N-terminal domain
InterPro IPR017853 Glycoside hydrolase, superfamily
Protein Ontology PR:000007837 neutral alpha-glucosidase AB
Graphical View of Protein Domain Structure
References (Earliest) J:40482 Arendt CW, et al., Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II. J Biol Chem. 1997 May 16;272(20):13117-25
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2147660

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory