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Ganab
Gene Detail
Symbol

Name
ID
Ganab
alpha glucosidase 2 alpha neutral subunit
MGI:1097667
Synonyms
G2an, GluII, mKIAA0088
Feature Type
protein coding gene
Genetic Map
Chromosome 19
5.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:8898090-8916663 bp, + strand
From Ensembl annotation of GRCm38

  18574 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5426  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: GANAB
Protein SuperFamily: lysosomal alpha-glucosidase
Gene Tree: Ganab

Human
homologs
GANAB, glucosidase, alpha; neutral AB
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23193
neXtProt AC: NX_Q14697

Human Synonyms: G2AN, GLUII

Human Chr (Location): 11q12.3; chr11:62624826-62646726 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(24) : Gene trapped(24)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ganab interacts with 163 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process carbohydrate metabolic process, metabolic process, ...
Component endoplasmic reticulum, extracellular exosome, ...
Function carbohydrate binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (187)    Tissues (94)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 187
cDNA source data(408)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ganab    NEW 
Molecular
reagents
All nucleic(409) cDNA(408) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000071650 (Evidence)
Entrez Gene 14376 (Evidence)
UniGene 3196
DFCI TC1778777, TC1614925, TC1605829, TC1603245, TC1586987, TC1574004
DoTS DT.94412045, DT.94412028, DT.94411986, DT.102558068, DT.101390641, DT.101148093, DT.94241778
NIA Mouse Gene Index U019133
EC 3.2.1.84
Consensus CDS Project CCDS29557.1
International Mouse Phenotyping Consortium Status Ganab
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071650 Ensembl Gene Model | MGI Sequence Detail 18574 C57BL/6J ±  kb
transcript ENSMUST00000096246 Ensembl | MGI Sequence Detail 3862 Not Applicable 
polypeptide ENSMUSP00000093965 Ensembl | MGI Sequence Detail 966 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011013 Galactose mutarotase-like domain
InterPro IPR000322 Glycoside hydrolase, family 31
InterPro IPR025887 Glycoside hydrolase family 31, N-terminal domain
InterPro IPR017853 Glycoside hydrolase, superfamily
Protein Ontology PR:000007837 neutral alpha-glucosidase AB
References
(Earliest) J:40482 Arendt CW, et al., Identification of the CD45-associated 116-kDa and 80-kDa proteins as the alpha- and beta-subunits of alpha-glucosidase II. J Biol Chem. 1997 May 16;272(20):13117-25
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2147660

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory