Eef1a1
Gene Detail

Symbol Name ID

Eef1a1 eukaryotic translation elongation factor 1 alpha 1 MGI:1096881

Synonyms

MGC:18758, MGC:27859, MGC:7551, MGC:8115, MGC:8209

Feature Type

protein coding gene

Genetic Map

Chromosome 9

43.65 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr9:78478449-78489151 bp, - strand From VEGA annotation of GRCm38   10703 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:100799  Vertebrate Homology Class
1 mouse; 1 rat; 1 rhesus macaque; 2 zebrafish

Protein SuperFamily: translation elongation factor Tu
Gene Tree: Eef1a1

Alleles and phenotypes

All alleles(77) : Targeted(1) Gene trapped(76)
Human Diseases Modeled Using Mouse Eef1a1 (1)    Alleles Annotated to Human Diseases(1)   

Gene Ontology (GO) classifications

All GO classifications: (18 annotations)

Process	protein homooligomerization, translation, ...
Component	cytoplasm, nucleus, ...
Function	GTPase activity, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (9 records)
Data Summary: Results (90)    Tissues (69)    Images (14)
Theiler Stages: 19, 21, 23, 28

Assay Type	Results
RNA in situ	44
RT-PCR	46

cDNA source data(55)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(58) cDNA(56) Primer pair(1) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000019692 (Evidence)
Ensembl Gene Model	ENSMUSG00000037742 (Evidence)
Entrez Gene	13627 (Evidence)
DoTS	DT.101371684, DT.101371734, DT.101371830, DT.101371843, DT.101371901, DT.101741357, DT.103600984, DT.110597064, DT.110597257, DT.110597266, DT.110597341, DT.110597348, DT.110597623, DT.110597737, DT.110597890, DT.87064849, DT.91396825, DT.94133783, DT.94292162, DT.94292268, DT.94292371, DT.94292429, DT.94292534, DT.97395407, DT.97395821, DT.97395914, DT.97395955, DT.97396052, DT.98132246, DT.99873017
Consensus CDS Project	CCDS40703.1
International Mouse Knockout Project Status	Eef1a1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000019692	VEGA Gene Model | MGI Sequence Detail	10703	C57BL/6J
transcript	OTTMUST00000047139	VEGA | MGI Sequence Detail	1794	Not Applicable
polypeptide	OTTMUSP00000021291	VEGA | MGI Sequence Detail	462	Not Applicable

All sequences(170) RefSeq(2) UniProt(8)

Polymorphisms

SNPs(10 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000795	Elongation factor, GTP-binding domain
InterPro	IPR004539	Translation elongation factor EF1A, eukaryotic/archaeal
InterPro	IPR009001	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
InterPro	IPR004160	Translation elongation factor EFTu/EF1A, C-terminal
InterPro	IPR004161	Translation elongation factor EFTu/EF1A, domain 2
InterPro	IPR009000	Translation elongation/initiation factor/Ribosomal, beta-barrel
Protein Ontology	PR:000006903	elongation factor 1-alpha 1

References

(Earliest) J:20252 Nagata S, et al., Polypeptide chain elongation factor 1 alpha (EF-1 alpha) from yeast: nucleotide sequence of one of the two genes for EF-1 alpha from Saccharomyces cerevisiae. EMBO J. 1984 Aug;3(8):1825-30
(Latest) J:175560 Lamberti A, et al., Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics. Biochimie. 2011 Oct;93(10):1738-46
All references(56)