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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Eef1a1
eukaryotic translation elongation factor 1 alpha 1
MGI:1096881
15 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Eef1a1tm1(FBXW7*)Iaai/Eef1a1+
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA 		decreased tumor latency J:200006
normal neoplasm J:200006
Eef1a1tm1Tcrl/Eef1a1+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S6/SvEvTac * C57BL/6 * CBA 		holoprosencephaly J:225273
lethality throughout fetal growth and development, incomplete penetrance J:225273
open neural tube J:225273
postnatal lethality, complete penetrance J:225273
spina bifida J:225273
Eef1a1tm1Tcrl/Eef1a1tm1Tcrl
involves: 129S6/SvEvTac * C57BL/6 		lethality, complete penetrance J:225273
Eef1a1tm2Arge/Eef1a1+
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA 		abnormal double-positive T cell morphology J:197167
increased acute lymphoblastic leukemia incidence J:197167
Eef1a1tm2Arge/Eef1a1+
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
involves: C57BL/6 * C57BL/6NTac 		abnormal bone marrow cell physiology J:196407
Col1a1/Col1a1+
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat/0
involves: C57BL/6J * FVB/NTac 		abnormal cued conditioning behavior J:297390
decreased anxiety-related response J:297390
Col1a1/Col1a1+
Sst/Sst+
involves: 129S4/SvJae * C57BL/6J 		normal behavior/neurological phenotype J:297390
impaired cued conditioning behavior J:297390
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory