Taz
Gene Detail

Symbol Name ID

Taz tafazzin MGI:109626

Synonyms

5031411C02Rik, 9130012G04Rik, G4.5

Feature Type

protein coding gene

Genetic Map

Chromosome X

37.95 cM, cytoband C1-C3
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

ChrX:74281912-74290151 bp, + strand From VEGA annotation of GRCm38   8240 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37264  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Taz

Human homologs

Human Homolog		TAZ, tafazzin
NCBI Gene ID		6901
neXtProt AC		NX_Q16635
Human Synonyms		BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1
Human Chr (Location)		Xq28; chrX:153639877-153650065 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TAZ

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	cardiac muscle contraction, cardiac muscle tissue development, ...
Component	mitochondrion, plasma membrane
Function	1-acylglycerophosphocholine O-acyltransferase activity

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (96)    Tissues (95)    Images (4)
Theiler Stages: 20, 22

Assay Type	Results
RNA in situ	94
RT-PCR	2

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) Genomic(6) cDNA(15) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000017668 (Evidence)
Ensembl Gene Model	ENSMUSG00000009995 (Evidence)
Entrez Gene	66826 (Evidence)
DFCI	TC1574015, TC1595701, TC1644521, TC1649884, TC1748776
NIA Mouse Gene Index	U019955
Consensus CDS Project	CCDS30224.1, CCDS53107.1, CCDS57764.1
International Mouse Knockout Project Status	Taz

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017668	VEGA Gene Model | MGI Sequence Detail	8240	C57BL/6J
transcript	OTTMUST00000046890	VEGA | MGI Sequence Detail	1786	Not Applicable
polypeptide	OTTMUSP00000021189	VEGA | MGI Sequence Detail	263	Not Applicable

All sequences(117) RefSeq(8) UniProt(14)

Polymorphisms

SNPs(38 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002123	Phospholipid/glycerol acyltransferase
InterPro	IPR000872	Tafazzin
Protein Ontology	PR:000016092	tafazzin

References

(Earliest) J:26634 Rivella S, et al., A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes. Genomics. 1995 Aug 10;28(3):377-82
(Latest) J:192726 Jang EJ, et al., TAZ suppresses NFAT5 activity through tyrosine phosphorylation. Mol Cell Biol. 2012 Dec;32(24):4925-32
All references(39)

Other accession IDs

MGD-MRK-39625, MGI:1914076, MGI:1926060, MGI:2147995, MGI:2148024