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Taz Gene Detail
Summary
  • Symbol
    Taz
  • Name
    tafazzin
  • Synonyms
    5031411C02Rik, 9130012G04Rik, G4.5
  • Feature Type
    protein coding gene
  • IDs
    MGI:109626
    NCBI Gene: 66826
  • Gene Overview
    MyGene.info: TAZ
Location & Maps
more
  • Sequence Map
    ChrX:74281912-74290151 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8240 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.95 cM, cytoband C1-C3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    TAZ, tafazzin
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TAZ, tafazzin
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1
  • Links
    NCBI Gene ID: 6901
    neXtProt AC: NX_Q16635

  • Chr Location
    Xq28; chrX:154411518-154421726 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 37264
    1 human;1 mouse;1 rat;1 rhesus macaque;1 cattle;1 dog;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: TAZ
  • Gene Tree
    Taz
Human Diseases
more
  • Diseases
    1 with human TAZ associations

Human Disease Mouse Models
       Barth Syndrome; BTHS   OMIM: 302060
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Targeted
    2
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017668 VEGA Gene Model | MGI Sequence Detail 8240 C57BL/6J ±  kb
transcript OTTMUST00000046890 VEGA | MGI Sequence Detail 1786 Not Applicable  
polypeptide OTTMUSP00000021189 VEGA | MGI Sequence Detail 263 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    42 from dbSNP Build 142
Protein
Information
less
  • UniProt
    14 Sequences
  • InterPro Domains
    IPR002123 Phospholipid/glycerol acyltransferase
    IPR000872 Tafazzin
Molecular
Reagents
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  • All nucleic 22
    Genomic 6
    cDNA 16

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-39625, MGI:1914076, MGI:1926060, MGI:2147995, MGI:2148024
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:26634 Rivella S, et al., A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes. Genomics. 1995 Aug 10;28(3):377-82
  • Latest
    J:227279 Zanconato F, et al., Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth. Nat Cell Biol. 2015 Sep;17(9):1218-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory