Sf3b4
Gene Detail

Symbol Name ID

Sf3b4 splicing factor 3b, subunit 4 MGI:109580

Synonyms

49kDa, MGC:36369, MGC:36564, Sap49, SF3b49

Feature Type

protein coding gene

Genetic Map

Chromosome 3

41.65 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:96172332-96177564 bp, + strand From VEGA annotation of GRCm38   5233 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; rat; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Sf3b4 ± 2 cM)

Gene Tree: Sf3b4

Human ortholog

SF3B4 splicing factor 3b, subunit 4, 49kDa NCBI Gene ID 10262
Human Synonyms: AFD1, Hsh49, SAP49, SF3b49
Human Chr1:149895211-149899702 bp, - strand Reference GRCh37.p2 Primary Assembly
Human Diseases Associated with Human SF3B4 (1)

Alleles and phenotypes

All alleles(28) : Targeted(1) Gene trapped(27)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	mRNA processing, RNA splicing
Component	nucleus, spliceosomal complex, ...
Function	nucleic acid binding, nucleotide binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (61)    Tissues (49)    Images (16)
Theiler Stages: 12, 16, 18, 19, 20, 21, 22, 23, 25, 28

Assay Type	Results
RNA in situ	45
Northern blot	14
RT-PCR	2

cDNA source data(74)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(75) cDNA(74) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000021896 (Evidence)
Ensembl Gene Model	ENSMUSG00000068856 (Evidence)
Entrez Gene	107701 (Evidence)
UniGene	219671
DFCI	TC1574620
DoTS	DT.532837, DT.97370559
Consensus CDS Project	CCDS17630.1
International Mouse Knockout Project Status	Sf3b4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021896	VEGA Gene Model | MGI Sequence Detail	5233	C57BL/6J
transcript	OTTMUST00000051999	VEGA | MGI Sequence Detail	1915	Not Applicable
polypeptide	OTTMUSP00000024556	VEGA | MGI Sequence Detail	424	Not Applicable

All sequences(28) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(37 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR012677	Nucleotide-binding, alpha-beta plait
InterPro	IPR000504	RNA recognition motif domain
Protein Ontology	PR:000014738	splicing factor 3B subunit 4

References

(Earliest) J:39334 Ruiz-Lozano P, et al., Developmental expression of the murine spliceosome-associated protein mSAP49. Dev Dyn. 1997 Apr;208(4):482-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)

Other accession IDs

MGD-MRK-39579