Kif21a
Gene Detail

Symbol Name ID

Kif21a kinesin family member 21A MGI:109188

Synonyms

mKIAA1708, N-5 kinesin

Feature Type

protein coding gene

Genetic Map

Chromosome 15

45.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr15:90933276-91049948 bp, - strand From NCBI annotation of GRCm38   116673 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:56761  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Kif21a

Human homologs

Human Homolog		KIF21A, kinesin family member 21A
NCBI Gene ID		55605
neXtProt AC		NX_Q7Z4S6
Human Synonyms		CFEOM1, FEOM1, FEOM3A
Human Chr (Location)		12q12; chr12:39687030-39837192 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human KIF21A

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	microtubule-based movement
Component	cell projection, cytoplasm, ...
Function	ATP binding, microtubule binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (125)    Tissues (49)    Images (40)
Theiler Stages: 6, 7, 9, 11, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
Immunohistochemistry	13
RNA in situ	78
Northern blot	25
Western blot	9

cDNA source data(118)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(120) cDNA(118) Primer pair(1) Other(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000022629 (Evidence)
Entrez Gene	16564 (Evidence)
UniGene	41379
DFCI	TC1575116, TC1594849, TC1602765, TC1616395
DoTS	DT.101185367, DT.101243299, DT.101394102, DT.101737488, DT.40138712
NIA Mouse Gene Index	U036548
Consensus CDS Project	CCDS37179.1, CCDS49706.1, CCDS49707.1, CCDS49708.1
International Mouse Knockout Project Status	Kif21a

Sequences

Length	Strain/Species
genomic	16564	NCBI Gene Model | MGI Sequence Detail	116673	C57BL/6J
transcript	NM_001109040	RefSeq | MGI Sequence Detail	6439	C57BL/6
polypeptide	Q9QXL2	UniProt | EBI | MGI Sequence Detail	1672	Not Applicable

All sequences(56) RefSeq(8) UniProt(7)

Polymorphisms

RFLP(1) : SNPs(818 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001752	Kinesin, motor domain
InterPro	IPR019821	Kinesin, motor region, conserved site
InterPro	IPR009053	Prefoldin
InterPro	IPR001680	WD40 repeat
InterPro	IPR019775	WD40 repeat, conserved site
InterPro	IPR017986	WD40-repeat-containing domain
InterPro	IPR015943	WD40/YVTN repeat-like-containing domain
Protein Ontology	PR:000009299	kinesin-like protein KIF21A

Graphical View of Protein Domain Structure

References

(Earliest) J:63692 Marszalek JR, et al., Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. J Cell Biol. 1999 May 3;145(3):469-79
(Latest) J:183941 Desai J, et al., Spatiotemporal expression pattern of KIF21A during normal embryonic development and in congenital fibrosis of the extraocular muscles type 1 (CFEOM1). Gene Expr Patterns. 2012 May;12(5-6):180-8
All references(35)

Other accession IDs

MGD-MRK-38232, MGI:2146087