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Kif21a
Gene Detail
Symbol

Name
ID
Kif21a
kinesin family member 21A
MGI:109188
Synonyms
mKIAA1708, N-5 kinesin
Feature Type
protein coding gene
Genetic Map
Chromosome 15
45.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr15:90933276-91049948 bp, - strand
From Ensembl annotation of GRCm38

  116673 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56761  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Kif21a

Human
homologs
Human Homolog KIF21A, kinesin family member 21A
NCBI Gene ID 55605
neXtProt AC  NX_Q7Z4S6
Human Synonyms  CFEOM1, FEOM1, FEOM3A
Human Chr (Location)  12q12; chr12:39293228-39443390 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human KIF21A
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Radiation induced(1) Targeted(2)
Genomic Mutations involving Kif21a (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Kif21a interacts with 282 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process ATP catabolic process, microtubule-based movement
Component cell projection, cytoplasm, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (125)    Tissues (50)    Images (42)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 13
RNA in situ 78
Northern blot 25
Western blot 9
cDNA source data(118)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(120) cDNA(118) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000022629 (Evidence)
Entrez Gene16564 (Evidence)
UniGene41379
DFCITC1575116, TC1594849, TC1616395, TC1602765
DoTSDT.40138712, DT.101737488, DT.101394102, DT.101185367, DT.101243299
NIA Mouse Gene IndexU036548
Consensus CDS ProjectCCDS37179.1, CCDS49706.1, CCDS49707.1, CCDS49708.1
International Mouse Knockout Project StatusKif21a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022629 Ensembl Gene Model | MGI Sequence Detail 116673 C57BL/6J ±  kb
transcript ENSMUST00000088614 Ensembl | MGI Sequence Detail 6439 Not Applicable 
polypeptide ENSMUSP00000085985 Ensembl | MGI Sequence Detail 1672 Not Applicable 

For the selected sequences
All sequences(100) RefSeq(46) UniProt(13)
Polymorphisms
RFLP(1) : SNPs within 2kb(1259 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001752 Kinesin, motor domain
InterPro IPR019821 Kinesin, motor region, conserved site
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR009053 Prefoldin
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000009299 kinesin-like protein KIF21A
References
(Earliest) J:63692 Marszalek JR, et al., Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. J Cell Biol. 1999 May 3;145(3):469-79
(Latest) J:183941 Desai J, et al., Spatiotemporal expression pattern of KIF21A during normal embryonic development and in congenital fibrosis of the extraocular muscles type 1 (CFEOM1). Gene Expr Patterns. 2012 May;12(5-6):180-8
All references(36)
Other
accession IDs
MGD-MRK-38232, MGI:2146087

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory