Kif21a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kif21a
kinesin family member 21A
MGI:109188

16 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kif21a^tm1.1Ece/Kif21a⁺ involves: 129S1/Sv * 129S4/SvJae	abnormal eye morphology	J:213171
	abnormal oculomotor nerve morphology	J:213171
	blepharoptosis	J:213171
Kif21a^tm1.1Ece/Kif21a^tm1.1Ece involves: 129S1/Sv * 129S4/SvJae	abnormal abducens nerve morphology	J:213171
	abnormal extraocular muscle morphology	J:213171
	abnormal eye morphology	J:213171
	abnormal innervation pattern to muscle	J:213171
	abnormal oculomotor nerve morphology	J:213171
	blepharoptosis	J:213171
	decreased motor neuron number	J:213171
Kif21a^tm1.1Ece/Kif21a^tm1.1Ece Tg(Isl1-EGFP)1Slp/0 involves: 129S1/Sv 129S4/SvJae * BALB/c * C57BL/6	abnormal abducens nerve morphology	J:213171
	abnormal axon extension	J:213171
	abnormal axon morphology	J:213171
	abnormal extraocular muscle morphology	J:213171
	abnormal oculomotor nerve morphology	J:213171
	increased neuron apoptosis	J:213171
	thin oculomotor nerve	J:213171
Kif21a^tm1.1Ece/Kif21a^tm3Ece involves: 129S1/Sv * 129S4/SvJae	abnormal extraocular muscle morphology	J:213171
Kif21a^{tm1b(EUCOMM)Hmgu}/Kif21a⁺ C57BL/6N-Kif21a^{tm1b(EUCOMM)Hmgu}/J	decreased fasting circulating glucose level	J:211773
Kif21a^{tm1b(EUCOMM)Hmgu}/Kif21a^{tm1b(EUCOMM)Hmgu} C57BL/6N-Kif21a^{tm1b(EUCOMM)Hmgu}/J	preweaning lethality, complete penetrance	J:211773
Kif21a^tm2Ece/? involves: 129S1/Sv * 129S4/SvJae	no abnormal phenotype detected	J:213171
Kif21a^tm3Ece/Kif21a⁺ involves: 129S1/Sv	no abnormal phenotype detected	J:213171
Kif21a^tm3Ece/Kif21a^tm3Ece involves: 129S1/Sv	neonatal lethality, complete penetrance	J:213171
Kif21a^tm3Ece/Kif21a^tm3Ece involves: 129S1/Sv	normal nervous system phenotype	J:213171

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23