Kif21a^tm2Ece
Targeted Allele Detail

Summary

• Symbol: Kif21a^tm2Ece
• Name: kinesin family member 21A; targeted mutation 2, Elizabeth C Engle
• MGI ID: MGI:5635265
• Synonyms: Kif21a^loxP
• Gene: Kif21a Location: Chr15:90817479-90934151 bp, - strand Genetic Position: Chr15, 45.86 cM
• Alliance: Kif21a^tm2Ece page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213171
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (No functional change)
• Mutation: Insertion
• A single loxP site was inserted into intron 19. (J:213171)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif21a Mutation: 81 strains or lines available

References

• Original: J:213171 Cheng L, et al., Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling. Neuron. 2014 Apr 16;82(2):334-49
• All: 1 reference(s)