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Npy2r
Gene Detail
Symbol

Name
ID
Npy2r
neuropeptide Y receptor Y2
MGI:108418
Synonyms
NPY-Y2 receptor
Feature Type
protein coding gene
Genetic Map
Chromosome 3
36.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr3:82538383-82548084 bp, - strand
From VEGA annotation of GRCm38

  9702 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:701  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 3 zebrafish

Protein SuperFamily: neuropeptide Y receptor 2
Gene Tree: Npy2r

Human
homologs
Human Homolog NPY2R, neuropeptide Y receptor Y2
NCBI Gene ID 4887
neXtProt AC  NX_P49146
Human Synonyms  NPY2-R
Human Chr (Location)  4q31; chr4:155173772-155217078 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit reduced food intake, body weight, and adiposity, elevated plasma pancreatic polypeptide levels, increased cancellous bone volume, and heightened sensitivity to pentobarbital-induced sedation.
 
Interactions
Npy2r interacts with 258 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (106)    Tissues (67)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 106
cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(7)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000043302 (Evidence)
Ensembl Gene ModelENSMUSG00000028004 (Evidence)
Entrez Gene18167 (Evidence)
UniGene1433
DFCITC1583767
DoTSDT.40167171, DT.110469563
NIA Mouse Gene IndexU024190
Consensus CDS ProjectCCDS57219.1, CCDS59646.1
International Mouse Knockout Project StatusNpy2r
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043302 VEGA Gene Model | MGI Sequence Detail 9702 C57BL/6J ±  kb
transcript OTTMUST00000113597 VEGA | MGI Sequence Detail 3325 Not Applicable 
polypeptide OTTMUSP00000063500 VEGA | MGI Sequence Detail 381 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(10) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001358 Neuropeptide Y2 receptor
InterPro IPR000611 Neuropeptide Y receptor family
Protein Ontology PR:000001493 neuropeptide Y receptor type 2
References
(Earliest) J:36684 Nakamura M, et al., Cloning and functional expression of a cDNA encoding a mouse type 2 neuropeptide Y receptor. Biochim Biophys Acta. 1996 Oct 23;1284(2):134-7
(Latest) J:204140 Loktev AV, et al., Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia. Cell Rep. 2013 Dec 12;5(5):1316-29
All references(93)
Other
accession IDs
MGD-MRK-37461

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory