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Npy2r
Gene Detail
Symbol

Name
ID
Npy2r
neuropeptide Y receptor Y2
MGI:108418
Synonyms
NPY-Y2 receptor
Feature Type
protein coding gene
Genetic Map
Chromosome 3
36.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr3:82538383-82548084 bp, - strand
From VEGA annotation of GRCm38

  9702 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:701  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 3 zebrafish

HCOP human homology predictions: NPY2R
Protein SuperFamily: neuropeptide Y receptor 2
Gene Tree: Npy2r

Human
homologs
NPY2R, neuropeptide Y receptor Y2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4887
neXtProt AC: NX_P49146

Human Synonyms: NPY2-R

Human Chr (Location): 4q31; chr4:155173754-155217096 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit reduced food intake, body weight, and adiposity, elevated plasma pancreatic polypeptide levels, increased cancellous bone volume, and heightened sensitivity to pentobarbital-induced sedation.
 
Interactions
Npy2r interacts with 257 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (106)    Tissues (67)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 106
cDNA source data(7)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100494553 ; ZFIN LOC100003852, npy2rl    NEW 
Molecular
reagents
All nucleic(8) Genomic(1) cDNA(7)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000043302 (Evidence)
Ensembl Gene Model ENSMUSG00000028004 (Evidence)
Entrez Gene 18167 (Evidence)
UniGene 1433
DFCI TC1583767
DoTS DT.110469563, DT.40167171
NIA Mouse Gene Index U024190
Consensus CDS Project CCDS57219.1, CCDS59646.1
International Mouse Phenotyping Consortium Status Npy2r
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000043302 VEGA Gene Model | MGI Sequence Detail 9702 C57BL/6J ±  kb
transcript OTTMUST00000113601 VEGA | MGI Sequence Detail 3364 Not Applicable 
polypeptide OTTMUSP00000063502 VEGA | MGI Sequence Detail 381 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(10) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001358 Neuropeptide Y2 receptor
InterPro IPR000611 Neuropeptide Y receptor family
Protein Ontology PR:000001493 neuropeptide Y receptor type 2
References
(Earliest) J:36684 Nakamura M, et al., Cloning and functional expression of a cDNA encoding a mouse type 2 neuropeptide Y receptor. Biochim Biophys Acta. 1996 Oct 23;1284(2):134-7
(Latest) J:220583 Nielsen JV, et al., Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex. Cereb Cortex. 2014 May;24(5):1216-29
All references(94)
Other
accession IDs
MGD-MRK-37461

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory