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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Npy2r
neuropeptide Y receptor Y2
MGI:108418
55 phenotypes from 4 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Npy2rem1(IMPC)H/Npy2rem1(IMPC)H
C57BL/6N-Npy2rem1(IMPC)H/H
abnormal locomotor behavior J:211773
enlarged spleen J:211773
increased spleen weight J:211773
Npy2rtm1.1Hhz/Npy2rtm1.1Hhz
involves: 129X1/SvJ
abnormal food intake J:129742
Npy2rtm1.1Hhz/Npy2rtm1.1Hhz
involves: 129X1/SvJ * BALB/cJ * C57BL/6
abnormal circulating pancreatic peptide level J:84570
abnormal eating behavior J:84570
abnormal trabecular bone morphology J:84570
decreased body weight J:84570
decreased osteoclast cell number J:84570
decreased white adipose tissue amount J:84570
increased trabecular bone thickness J:84570
Npy2rtm1.1Hhz/Npy2rtm1.1Hhz
involves: 129X1/SvJ * C57BL/6
abnormal circulating pancreatic peptide level J:77345
abnormal eating behavior J:77345
abnormal olfactory sensory neuron morphology J:132859
abnormal postnatal subventricular zone morphology J:132859
abnormal rostral migratory stream morphology J:132859
abnormal spatial learning J:121312
abnormal testosterone level J:129609
abnormal trabecular bone morphology J:97455
decreased anxiety-related response J:96222
decreased body weight J:77345
decreased circulating corticosterone level J:107169
decreased circulating insulin level J:77345
decreased neuronal precursor cell number J:132859
decreased white adipose tissue amount J:77345
impaired long-term object recognition memory J:121312
increased circulating insulin-like growth factor I level J:129609
increased fluid intake J:115774
increased growth hormone level J:129609
increased susceptibility to pharmacologically induced seizures J:124729
increased susceptibility to xenobiotic induced morbidity/mortality J:124729
increased trabecular bone thickness J:97455
Npy2rtm1Hhz/Npy2rtm1Hhz
involves: 129X1/SvJ * C57BL/6
abnormal circulating hormone level J:77345
abnormal circulating insulin level J:77345
abnormal circulating pancreatic peptide level J:77345
abnormal food intake J:77345
abnormal trabecular bone morphology J:97455
normal adipose tissue phenotype J:77345
decreased body weight J:77345
decreased osteoclast cell number J:97455
normal homeostasis/metabolism phenotype J:77345
increased bone mineralization J:97455
increased bone ossification J:97455
increased circulating corticosterone level J:77345, J:97455
increased trabecular bone thickness J:97455
Npy2rtm1Pern/Npy2rtm1Pern
involves: 129
abnormal righting response J:71826
abnormal sleep duration J:71826
Npy2rtm1Pern/Npy2rtm1Pern
involves: 129/Sv * BALB/c
abnormal circadian regulation of heart rate J:57961
abnormal food intake J:57961
decreased energy expenditure J:57961
decreased locomotor activity J:57961
increased body weight J:57961
increased total fat pad weight J:57961
polyphagia J:57961
Npy2rtm1Pern/Npy2rtm1Pern
involves: 129/Sv * BALB/cJ
alcohol aversion J:102430
increased fluid intake J:102430
Npytm1(rtTA,tetO-cre/EGFP)Snby/Npy+
Npy2rtm1Hhz/Npy2rtm1Hhz
involves: 129X1/SvJ * C57BL/6
abnormal glucose homeostasis J:162000
abnormal locomotor activation J:162000
normal behavior/neurological phenotype J:162000
decreased body temperature J:162000
decreased white adipose tissue mass J:162000
normal growth/size/body region phenotype J:162000
increased body fat mass J:162000
increased liver triglyceride level J:162000
increased oxygen consumption J:162000
increased susceptibility to weight gain J:162000
increased trabecular bone volume J:162000
increased white adipose tissue mass J:162000
normal renal/urinary system phenotype J:162000

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory