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Ywhag Gene Detail
Summary
  • Symbol
    Ywhag
  • Name
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
  • Synonyms
    14-3-3 gamma, D7Bwg1348e
  • Feature Type
    protein coding gene
  • IDs
    MGI:108109
    NCBI Gene: 22628
  • Gene Overview
    MyGene.info: YWHAG
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:135908409-135934616 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 75.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108109
protein coding gene Chr5:135908379-135934641 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030193
protein coding gene Chr5:140508210-140538336 (-)
A/J MGP_AJ_G0030161
protein coding gene Chr5:134468616-134494523 (-)
AKR/J MGP_AKRJ_G0030094
protein coding gene Chr5:138815425-138843039 (-)
BALB/cJ MGP_BALBcJ_G0030171
protein coding gene Chr5:135820185-135850070 (-)
C3H/HeJ MGP_C3HHeJ_G0029887
protein coding gene Chr5:139419747-139447453 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030624
protein coding gene Chr5:145743847-145770592 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027846
protein coding gene Chr5:128754943-128781837 (-)
CAST/EiJ MGP_CASTEiJ_G0029297
protein coding gene Chr5:138824783-138852060 (-)
CBA/J MGP_CBAJ_G0029857
protein coding gene Chr5:151397386-151432758 (-)
DBA/2J MGP_DBA2J_G0030008
protein coding gene Chr5:134366103-134391869 (-)
FVB/NJ MGP_FVBNJ_G0029963
protein coding gene Chr5:133513919-133542050 (-)
LP/J MGP_LPJ_G0030097
protein coding gene Chr5:140933023-140960604 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029995
protein coding gene Chr5:154415867-154442654 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030664
protein coding gene Chr5:138610850-138640076 (-)
PWK/PhJ MGP_PWKPhJ_G0029010
protein coding gene Chr5:133425795-133452491 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028846
protein coding gene Chr5:136161926-136188126 (-)
WSB/EiJ MGP_WSBEiJ_G0029370
protein coding gene Chr5:139341868-139368027 (-)



Homology
more
  • Human Ortholog
    YWHAG, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  • Vertebrate Orthologs
    9
  • Human Ortholog
    YWHAG, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
    Orthology source: HomoloGene, HGNC
  • Synonyms
    14-3-3GAMMA, EIEE56, PPP1R170
  • Links
    NCBI Gene ID: 7532
    neXtProt AC: NX_P61981
    UniProt: P61981

  • Chr Location
    7q11.23; chr7:76326791-76359025 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human YWHAG associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Homozygous null mutants appear normal and exhibit unchanged survival rates after inoculation with pathological prion protein.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051391 Ensembl Gene Model | MGI Sequence Detail 26208 C57BL/6J ±  kb
transcript ENSMUST00000198270 Ensembl | MGI Sequence Detail 1610 Not Applicable  
polypeptide ENSMUSP00000143631 Ensembl | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 13
    Primer pair 2
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-34146, MGD-MRK-37146, MGI:106452
References
more
  • Summaries
    All 54
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 14
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:255082 Kurogi S, et al., Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. Sci Rep. 2017 Jan 20;7:40692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory