Wnt10a
Gene Detail

Symbol Name ID

Wnt10a wingless related MMTV integration site 10a MGI:108071

Feature Type

protein coding gene

Genetic Map

Chromosome 1

38.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:74791516-74804179 bp, + strand From VEGA annotation of GRCm38   12664 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22525  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt10a

Human homologs

Human Homolog		WNT10A, wingless-type MMTV integration site family, member 10A
NCBI Gene ID		80326
neXtProt AC		NX_Q9GZT5
Human Synonyms		OODD, SSPS, STHAG4
Human Chr (Location)		2q35; chr2:219745255-219758651 (+)  GRCh37.p10
Disease Associations		(3) Diseases Associated with Human WNT10A

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (24 annotations)

Process	cell-cell signaling, cell fate commitment, ...
Component	extracellular region, extracellular space, ...
Function	frizzled binding, receptor binding

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (49 records)
Data Summary: Results (362)    Tissues (257)    Images (92)
Theiler Stages: 1, 2, 3, 4, 5, 8, 9, 11, 13, 15, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	267
Northern blot	61
RT-PCR	32
RNase protection	2

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) Genomic(1) cDNA(14) Primer pair(8) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000020879 (Evidence)
Ensembl Gene Model	ENSMUSG00000026167 (Evidence)
Entrez Gene	22409 (Evidence)
UniGene	5130
DFCI	TC1588606
DoTS	DT.55281733
NIA Mouse Gene Index	U000462
Consensus CDS Project	CCDS15057.1
International Mouse Knockout Project Status	Wnt10a

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020879	VEGA Gene Model | MGI Sequence Detail	12664	C57BL/6J
transcript	OTTMUST00000049359	VEGA | MGI Sequence Detail	2468	Not Applicable
polypeptide	OTTMUSP00000022850	VEGA | MGI Sequence Detail	417	Not Applicable

All sequences(17) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(19 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR005817	Wnt
InterPro	IPR013302	Wnt-10 protein
InterPro	IPR018161	Wnt protein, conserved site
Protein Ontology	PR:000017436	protein Wnt-10a

References

(Earliest) J:36010 Wang J, et al., Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults. Oncogene. 1996 Oct 3;13(7):1537-44
(Latest) J:187747 Miyoshi H, et al., Wnt5a potentiates TGF-beta signaling to promote colonic crypt regeneration after tissue injury. Science. 2012 Oct 5;338(6103):108-13
All references(80)

Other accession IDs

MGD-MRK-37108