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Wnt10a
Gene Detail
 Symbol
Name
ID
Wnt10a
wingless-type MMTV integration site family, member 10A
MGI:108071
Feature Type protein coding gene
Genetic Map
Chromosome 1
38.54 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:74791516-74804179 bp, + strand
From VEGA annotation of GRCm38

  12664 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22525  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: int-1 transforming protein
Gene Tree: Wnt10a

Human
homologs
Human Homolog WNT10A, wingless-type MMTV integration site family, member 10A
NCBI Gene ID 80326
neXtProt AC  NX_Q9GZT5
Human Synonyms  OODD, SSPS, STHAG4
Human Chr (Location)  2q35; chr2:218880533-218893929 (+)  GRCh38
Disease Associations  (3) Diseases Associated with Human WNT10A
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Wnt10a interacts with 73 markers (Mir19a, Mir24-1, Mir24-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process cell-cell signaling, cell fate commitment, ...
Component extracellular region, extracellular space, ...
Function frizzled binding, receptor binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (52 records)
Data Summary: Results (680)    Tissues (469)    Images (105)
Theiler Stages: 1, 2, 3, 5, 8, 9, 11, 13, 15, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 591
Northern blot 61
RT-PCR 26
RNase protection 2
cDNA source data(11)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) Genomic(1) cDNA(16) Primer pair(8) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020879 (Evidence)
Ensembl Gene ModelENSMUSG00000026167 (Evidence)
Entrez Gene22409 (Evidence)
UniGene5130
DFCITC1588606
DoTSDT.55281733
NIA Mouse Gene IndexU000462
Consensus CDS ProjectCCDS15057.1
International Mouse Knockout Project StatusWnt10a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020879 VEGA Gene Model | MGI Sequence Detail 12664 C57BL/6J ±  kb
transcript OTTMUST00000049359 VEGA | MGI Sequence Detail 2468 Not Applicable 
polypeptide OTTMUSP00000022850 VEGA | MGI Sequence Detail 417 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005817 Wnt
InterPro IPR013302 Wnt-10 protein
InterPro IPR018161 Wnt protein, conserved site
Protein Ontology PR:000017436 protein Wnt-10a
References (Earliest) J:36010 Wang J, et al., Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults. Oncogene. 1996 Oct 3;13(7):1537-44
(Latest) J:207612 Zhang L, et al., Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development. Dev Biol. 2014 Mar 1;387(1):64-72
All references(85)
Other
accession IDs
MGD-MRK-37108

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory