Symbol
Name
ID

Wnt10a
wingless-type MMTV integration site family, member 10A
MGI:108071

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes

Sparse scalp hair

Aplasia of the maxilla

Bird-like facies

Short face

Eclabion

Abnormal dental morphology

Short dental root

Taurodontia

Peg-shaped maxillary lateral incisors

Abnormal primary molar morphology

Microdontia

Agenesis of central incisor

Agenesis of lateral incisor

Agenesis of maxillary lateral incisor

Agenesis of permanent teeth

Tooth agenesis

Anodontia

Hypodontia

Oligodontia

Oligodontia of primary teeth

Selective tooth agenesis

Agenesis of molar

Agenesis of permanent molar

Agenesis of first permanent molar tooth

Agenesis of premolar

Agenesis of mandibular premolar

Abnormality of canine

Delayed eruption of teeth

Delayed eruption of permanent teeth

Enamel hypoplasia

Hypoplasia of teeth

Abnormality of primary teeth

Premature loss of primary teeth

Dental malocclusion

Widely spaced teeth

Orofacial cleft

Impaired mastication

Aplasia/Hypoplasia of the eyebrow

Sparse eyebrow

Short eyelashes

Multiple eyelid margin cysts

Disease(s) Associated with WNT10A

Schopf-Schulz-Passarge syndrome

tooth agenesis

Mouse Phenotypes

abnormal alveolar process morphology

dental pulp stones

taurodontia

abnormal incisor morphology

abnormal molar morphology

abnormal molar crown morphology

abnormal molar cusp morphology

abnormal molar root morphology

absent molars

small molars

supernumerary molars

abnormal dentin mineralization

abnormal dentin morphology

abnormal tooth root resorption

abnormal tongue morphology

abnormal filiform papillae morphology

abnormal fungiform papillae morphology

abnormal gustatory papilla taste bud morphology

Availability

Mouse Genotype

Wnt10a^{tm1.1(KOMP)Vlcg}/Wnt10a^{tm1.1(KOMP)Vlcg}

Wnt10a^tm1.1Smr/Wnt10a^tm1.1Smr

Wnt10a^tm1Smr/Wnt10a^tm1Smr
Tg(KRT14-cre)#Smr/0 (conditional)

Tg(KRT5-rtTA)#Glk/0
Tg(tetO-cre)1Jaw/0
Wnt10a^tm1Smr/Wnt10a^tm1Smr (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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