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Siah1b Gene Detail
Summary
  • Symbol
    Siah1b
  • Name
    siah E3 ubiquitin protein ligase 1B
  • Synonyms
    Sinh1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:108063
    NCBI Gene: 20438
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:164070705-164076493 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 76.11 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108063
protein coding gene ChrX:164070703-164076493 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036250
protein coding gene ChrX:162144213-162149992 (-)
A/J MGP_AJ_G0036220
protein coding gene ChrX:161313280-161323411 (-)
AKR/J MGP_AKRJ_G0036148
protein coding gene ChrX:166504068-166509847 (-)
BALB/cJ MGP_BALBcJ_G0036213
protein coding gene ChrX:159315981-159321760 (-)
C3H/HeJ MGP_C3HHeJ_G0035920
protein coding gene ChrX:162494383-162500162 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036736
protein coding gene ChrX:166899050-166904837 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031346
protein coding gene Chr8:78280089-78284417 (-)
CAST/EiJ MGP_CASTEiJ_G0035208
protein coding gene ChrX:141468490-141473871 (-)
CBA/J MGP_CBAJ_G0035894
protein coding gene ChrX:171725873-171731652 (-)
DBA/2J MGP_DBA2J_G0036060
protein coding gene ChrX:160209229-160215655 (-)
FVB/NJ MGP_FVBNJ_G0035992
protein coding gene ChrX:159341748-159347444 (-)
LP/J MGP_LPJ_G0036145
protein coding gene ChrX:163283038-163288817 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036024
protein coding gene ChrX:180412066-180422143 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034424
protein coding gene Chr8:86743911-86747810 (-)
PWK/PhJ MGP_PWKPhJ_G0034906
protein coding gene ChrX:138253938-138261254 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034727
protein coding gene ChrX:141972816-141977910 (-)
WSB/EiJ MGP_WSBEiJ_G0035343
protein coding gene ChrX:159600900-159606070 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Primary mouse embryonic fibroblasts hemizygous for a targeted allele show no apparent alterations in Trp53-mediated responses or mitotic progression.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040749 Ensembl Gene Model | MGI Sequence Detail 5789 C57BL/6J ±  kb
transcript ENSMUST00000037928 Ensembl | MGI Sequence Detail 1783 Not Applicable  
polypeptide ENSMUSP00000043215 Ensembl | MGI Sequence Detail 282 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 8
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-14420, MGD-MRK-37100, MGI:2147835
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:12699 Della NG, et al., Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina). Development. 1993 Apr;117(4):1333-43
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory