Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including identical protein binding activity; ubiquitin conjugating enzyme binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including canonical Wnt signaling pathway; positive regulation of intrinsic apoptotic signaling pathway; and protein destabilization. Predicted to be located in cytosol; early endosome; and nucleus. Predicted to be part of beta-catenin destruction complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human SIAH1 (siah E3 ubiquitin protein ligase 1).