Klc2
Gene Detail

Symbol Name ID

Klc2 kinesin light chain 2 MGI:107953

Synonyms

8030455F02Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 19

4.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr19:5107746-5118560 bp, - strand From VEGA annotation of GRCm38   10815 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22468  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: kinesin light chain
Gene Tree: Klc2

Human homologs

Human Homolog		KLC2, kinesin light chain 2
NCBI Gene ID		64837
neXtProt AC		NX_Q9H0B6
Human Chr (Location)		11q13.2; chr11:66024765-66035332 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	axon cargo transport, microtubule-based movement
Component	ciliary rootlet, cytoplasm, ...
Function	kinesin binding, microtubule motor activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(53)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(53) cDNA(53)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000016355 (Evidence)
Ensembl Gene Model	ENSMUSG00000024862 (Evidence)
Entrez Gene	16594 (Evidence)
UniGene	271648
Consensus CDS Project	CCDS37889.1
International Mouse Knockout Project Status	Klc2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000016355	VEGA Gene Model | MGI Sequence Detail	10815	C57BL/6J
transcript	OTTMUST00000039332	VEGA | MGI Sequence Detail	3169	Not Applicable
polypeptide	OTTMUSP00000017579	VEGA | MGI Sequence Detail	619	Not Applicable

All sequences(55) RefSeq(3) UniProt(4)

Polymorphisms

RFLP(1) : SNPs(28 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002151	Kinesin light chain
InterPro	IPR015792	Kinesin light chain repeat
InterPro	IPR015390	Rabaptin, GTPase-Rab5 binding domain
InterPro	IPR011990	Tetratricopeptide-like helical
InterPro	IPR019734	Tetratricopeptide repeat
InterPro	IPR013026	Tetratricopeptide repeat-containing domain
InterPro	IPR001440	Tetratricopeptide TPR-1
InterPro	IPR013105	Tetratricopeptide TPR2
Protein Ontology	PR:000009350	kinesin light chain 2

References

(Earliest) J:33932 Lamerdin JE, et al., Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes. Genomics. 1996 Jun 15;34(3):399-409
(Latest) J:180026 Dodding MP, et al., A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome. EMBO J. 2011 Nov 16;30(22):4523-38
All references(40)

Other accession IDs

MGD-MRK-36533, MGI:2147719, MGI:2447825