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Klc2
Gene Detail
 Symbol
Name
ID
Klc2
kinesin light chain 2
MGI:107953
Synonyms 8030455F02Rik
Feature Type protein coding gene
Genetic Map
Chromosome 19
4.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr19:5107746-5118560 bp, - strand
From VEGA annotation of GRCm38

  10815 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22468  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: kinesin light chain
Gene Tree: Klc2

Human
homologs
Human Homolog KLC2, kinesin light chain 2
NCBI Gene ID 64837
neXtProt AC  NX_Q9H0B6
Human Chr (Location)  11q13.2; chr11:66257294-66267861 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klc2 interacts with 204 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process axon cargo transport, microtubule-based movement
Component cell, ciliary rootlet, ...
Function kinesin binding, microtubule motor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(53)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(53) cDNA(53)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016355 (Evidence)
Ensembl Gene ModelENSMUSG00000024862 (Evidence)
Entrez Gene16594 (Evidence)
UniGene271648
PDB3ZFW
Consensus CDS ProjectCCDS37889.1
International Mouse Knockout Project StatusKlc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016355 VEGA Gene Model | MGI Sequence Detail 10815 C57BL/6J ±  kb
transcript OTTMUST00000039332 VEGA | MGI Sequence Detail 3169 Not Applicable 
polypeptide OTTMUSP00000017579 VEGA | MGI Sequence Detail 619 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(5) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(35 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002151 Kinesin light chain
InterPro IPR015792 Kinesin light chain repeat
InterPro IPR015390 Rabaptin, GTPase-Rab5 binding domain
InterPro IPR011990 Tetratricopeptide-like helical
InterPro IPR019734 Tetratricopeptide repeat
InterPro IPR013026 Tetratricopeptide repeat-containing domain
InterPro IPR001440 Tetratricopeptide TPR-1
InterPro IPR013105 Tetratricopeptide TPR2
Protein Ontology PR:000009350 kinesin light chain 2
References (Earliest) J:33932 Lamerdin JE, et al., Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes. Genomics. 1996 Jun 15;34(3):399-409
(Latest) J:180026 Dodding MP, et al., A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome. EMBO J. 2011 Nov 16;30(22):4523-38
All references(42)
Other
accession IDs
MGD-MRK-36533, MGI:2147719, MGI:2447825

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory