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Ifna4 Gene Detail
Summary
  • Symbol
    Ifna4
  • Name
    interferon alpha 4
  • Synonyms
    Ifa4
  • Feature Type
    protein coding gene
  • IDs
    MGI:107664
    NCBI Gene: 15967
  • Member of
    Ifna cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr4:88841861-88842421 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 42.03 cM
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107664
protein coding gene Chr4:88841816-88842459 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028437
protein coding gene Chr4:88744878-88745438 (+)
A/J MGP_AJ_G0028399
protein coding gene Chr4:85646921-85647481 (+)
AKR/J MGP_AKRJ_G0028346
protein coding gene Chr4:87760156-87760716 (+)
BALB/cJ MGP_BALBcJ_G0028417
protein coding gene Chr4:85859859-85860419 (+)
C3H/HeJ MGP_C3HHeJ_G0028130
protein coding gene Chr4:88487279-88487839 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028857
protein coding gene Chr4:92134849-92135409 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027571
protein coding gene Chr4:86323128-86323688 (+)
CBA/J MGP_CBAJ_G0028100
protein coding gene Chr4:94973444-94974004 (+)
DBA/2J MGP_DBA2J_G0028250
protein coding gene Chr4:85405947-85406507 (+)
FVB/NJ MGP_FVBNJ_G0028217
protein coding gene Chr4:84336391-84336951 (+)
LP/J MGP_LPJ_G0028349
protein coding gene Chr4:89038802-89039362 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028246
protein coding gene Chr4:99950002-99950562 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028894
protein coding gene Chr4:87904436-87904994 (+)
PWK/PhJ MGP_PWKPhJ_G0027295
protein coding gene Chr4:83695265-83695825 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0027649
protein coding gene Chr4:88104005-88104565 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Ifna4
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070904 Ensembl Gene Model | MGI Sequence Detail 561 C57BL/6J ±  kb
transcript ENSMUST00000094973 Ensembl | MGI Sequence Detail 561 Not Applicable  
polypeptide ENSMUSP00000092581 Ensembl | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR000471 Interferon alpha/beta/delta
Molecular
Reagents
less
  • All nucleic 13
    Genomic 6
    cDNA 6
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-11205, MGD-MRK-36239
References
more
  • Summaries
    All 31
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:7878 Zwarthoff EC, et al., Organization, structure and expression of murine interferon alpha genes. Nucleic Acids Res. 1985 Feb 11;13(3):791-804
  • Latest
    J:240213 Liu TT, et al., LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner. J Immunol. 2016 Jun 15;196(12):5101-11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory