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Ifna5 Gene Detail
Summary
  • Symbol
    Ifna5
  • Name
    interferon alpha 5
  • Synonyms
    Ifa5
  • Feature Type
    protein coding gene
  • IDs
    MGI:107663
    NCBI Gene: 15968
  • Member of
    Ifna cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr4:88753762-88754331 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 42.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107663
protein coding gene Chr4:88753762-88754331 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028436
protein coding gene Chr4:88705187-88705885 (+)
A/J MGP_AJ_G0028397
protein coding gene Chr4:85626208-85626829 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0028856
protein coding gene Chr4:92124419-92124988 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027564
protein coding gene Chr4:86129823-86131059 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0028216
protein coding gene Chr4:84330100-84330669 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0028893
protein coding gene Chr4:87896610-87897179 (+)
PWK/PhJ MGP_PWKPhJ_G0027287
protein coding gene Chr4:83533009-83533535 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0027642
protein coding gene Chr4:87915731-87916250 (-)



Homology
more
  • Human Ortholog
    IFNA10, interferon alpha 10
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFNA10, interferon alpha 10
  • Synonyms
    IFN-alphaC
  • Links
    NCBI Gene ID: 3446
    neXtProt AC: NX_P01566
    UniProt: P01566

  • Chr Location
    9p21.3; chr9:21206181-21207143 (-)  GRCh38.p7

  • Human Ortholog
    IFNA13, interferon alpha 13
  • Links
    NCBI Gene ID: 3447
    neXtProt AC: NX_P01562
    UniProt: P01562

  • Chr Location
    9p21.3; chr9:21367372-21368076 (-)  GRCh38.p7

  • Human Ortholog
    IFNA14, interferon alpha 14
  • Synonyms
    IFN-alphaH, LEIF2H
  • Links
    NCBI Gene ID: 3448
    neXtProt AC: NX_P01570
    UniProt: P01570

  • Chr Location
    9p21.3; chr9:21239202-21239979 (-)  GRCh38.p7

  • Human Ortholog
    IFNA16, interferon alpha 16
  • Synonyms
    IFN-alpha-16, IFN-alphaO
  • Links
    NCBI Gene ID: 3449
    neXtProt AC: NX_P05015
    UniProt: P05015

  • Chr Location
    9p21.3; chr9:21216373-21217311 (-)  GRCh38.p7

  • Human Ortholog
    IFNA17, interferon alpha 17
  • Synonyms
    IFNA, IFN-alphaI, INFA, LEIF2C1
  • Links
    NCBI Gene ID: 3451
    neXtProt AC: NX_P01571
    UniProt: P01571

  • Chr Location
    9p21.3; chr9:21227243-21228222 (-)  GRCh38.p7

  • Human Ortholog
    IFNA2, interferon alpha 2
  • Synonyms
    IFNA, IFNA2B, IFN-alpha-2, IFN-alphaA, leIF A
  • Links
    NCBI Gene ID: 3440
    neXtProt AC: NX_P01563
    UniProt: P01563

  • Chr Location
    9p21.3; chr9:21384255-21385397 (-)  GRCh38.p7

  • Human Ortholog
    IFNA21, interferon alpha 21
  • Synonyms
    IFN-alphaI, leIF-F, LeIF F
  • Links
    NCBI Gene ID: 3452
    neXtProt AC: NX_P01568
    UniProt: P01568

  • Chr Location
    9p21.3; chr9:21165637-21166660 (-)  GRCh38.p7

  • Human Ortholog
    IFNA4, interferon alpha 4
  • Synonyms
    IFN-alpha4a, INFA4
  • Links
    NCBI Gene ID: 3441
    neXtProt AC: NX_P05014
    UniProt: P05014

  • Chr Location
    9p21.3; chr9:21186618-21187599 (-)  GRCh38.p7

  • Human Ortholog
    IFNA6, interferon alpha 6
  • Synonyms
    IFN-alphaK
  • Links
    NCBI Gene ID: 3443
    neXtProt AC: NX_P05013
    UniProt: P05013

  • Chr Location
    9p21.3; chr9:21350318-21350887 (-)  GRCh38.p7

  • Human Ortholog
    IFNA7, interferon alpha 7
  • Synonyms
    IFNA-J, IFN-alphaJ
  • Links
    NCBI Gene ID: 3444
    neXtProt AC: NX_P01567
    UniProt: P01567

  • Chr Location
    9p21.3; chr9:21201469-21202205 (-)  GRCh38.p7

  • Human Ortholog
    IFNA8, interferon alpha 8
  • Synonyms
    IFN-alphaB
  • Links
    NCBI Gene ID: 3445
    neXtProt AC: NX_P32881
    UniProt: P32881

  • Chr Location
    9p21.3; chr9:21409147-21410185 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Ifna5
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15968 NCBI Gene Model | MGI Sequence Detail 570 C57BL/6J ±  kb
transcript NM_010505 RefSeq | MGI Sequence Detail 570 Not Specified  
polypeptide P07349 UniProt | EBI | MGI Sequence Detail 189 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR000471 Interferon alpha/beta/delta
Molecular
Reagents
less
  • All nucleic 12
    Genomic 7
    cDNA 3
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11206, MGD-MRK-36238
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:7878 Zwarthoff EC, et al., Organization, structure and expression of murine interferon alpha genes. Nucleic Acids Res. 1985 Feb 11;13(3):791-804
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory