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Ifna5 Gene Detail
Summary
  • Symbol
    Ifna5
  • Name
    interferon alpha 5
  • Synonyms
    Ifa5
  • Feature Type
    protein coding gene
  • IDs
    MGI:107663
    NCBI Gene: 15968
  • Member of
    Ifna cluster
  • Gene Overview
    MyGene.info: IFNA4
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr4:88835525-88836094 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 42.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107663
protein coding gene Chr4:88835525-88836094 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028436
protein coding gene Chr4:88705187-88705885 (+)
A/J MGP_AJ_G0028397
protein coding gene Chr4:85626208-85626829 (+)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0028856
protein coding gene Chr4:92124419-92124988 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027564
protein coding gene Chr4:86129823-86131059 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0028216
protein coding gene Chr4:84330100-84330669 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0028893
protein coding gene Chr4:87896610-87897179 (+)
PWK/PhJ MGP_PWKPhJ_G0027287
protein coding gene Chr4:83533009-83533535 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0027642
protein coding gene Chr4:87915731-87916250 (-)



Homology
more
  • Human Ortholog
    IFNA4, interferon alpha 4
  • Vertebrate Orthologs
    25
  • Human Ortholog
    IFNA4, interferon alpha 4
    Orthology source: HomoloGene
  • Synonyms
    IFN-alpha4a, INFA4
  • Links
    NCBI Gene ID: 3441
    neXtProt AC: NX_P05014
    UniProt: P05014

  • Chr Location
    9p21.3; chr9:21186618-21187599 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Ifna5
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15968 NCBI Gene Model | MGI Sequence Detail 570 C57BL/6J ±  kb
transcript NM_010505 RefSeq | MGI Sequence Detail 570 Not Specified  
polypeptide P07349 UniProt | EBI | MGI Sequence Detail 189 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR000471 Interferon alpha/beta/delta
Molecular
Reagents
less
  • All nucleic 12
    Genomic 7
    cDNA 3
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-11206, MGD-MRK-36238
References
more
  • Summaries
    All 23
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:7878 Zwarthoff EC, et al., Organization, structure and expression of murine interferon alpha genes. Nucleic Acids Res. 1985 Feb 11;13(3):791-804
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory