Ifngr1
Gene Detail

Symbol Name ID

Ifngr1 interferon gamma receptor 1 MGI:107655

Synonyms

CD119, Ifgr, IFN-gammaR, IFN-gamma R, Ifngr, Nktar

Feature Type

protein coding gene

Genetic Map

Chromosome 10

8.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(13)

Sequence Map

Chr10:19591949-19610229 bp, + strand From VEGA annotation of GRCm38   18281 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:359  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: interferon gamma receptor
Gene Tree: Ifngr1

Human homologs

Human Homolog		IFNGR1, interferon gamma receptor 1
NCBI Gene ID		3459
neXtProt AC		NX_P15260
Human Synonyms		CD119, IFNGR
Human Chr (Location)		6q23.3; chr6:137518621-137540567 (-)  GRCh37.p10
Disease Associations		(4) Diseases Associated with Human IFNGR1

Alleles and phenotypes

All alleles(4) : Targeted(4)
 

Mice homozygous for a mutant allele exhibit increased susceptibility to viral infection and experimental autoimmune uveoretinitis.

 
Phenotype Images(1)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Component	dendrite, endoplasmic reticulum, ...
Function	cytokine binding

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (200)    Tissues (13)    Images (48)
Theiler Stages: 23

Assay Type	Results
RNA in situ	200

cDNA source data(112)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(112) cDNA(112)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000035345 (Evidence)
Ensembl Gene Model	ENSMUSG00000020009 (Evidence)
Entrez Gene	15979 (Evidence)
UniGene	549
DFCI	TC1575830, TC1593432, TC1673148
DoTS	DT.534483
NIA Mouse Gene Index	U011310
Consensus CDS Project	CCDS35856.1
International Mouse Knockout Project Status	Ifngr1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035345	VEGA Gene Model | MGI Sequence Detail	18281	C57BL/6J
transcript	OTTMUST00000090213	VEGA | MGI Sequence Detail	2112	Not Applicable
polypeptide	OTTMUSP00000049447	VEGA | MGI Sequence Detail	477	Not Applicable

All sequences(60) RefSeq(2) UniProt(7)

Polymorphisms

RFLP(1) : SNPs(88 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003961	Fibronectin, type III
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR008355	Interferon gamma receptor alpha subunit
InterPro	IPR021126	Interferon gamma receptor, poxvirus/mammal
Protein Ontology	PR:000001361	interferon gamma receptor alpha chain

References

(Earliest) J:8684 Mariano TM, et al., The mouse immune interferon receptor gene is located on chromosome 10. J Biol Chem. 1987 Apr 25;262(12):5812-4
(Latest) J:193821 Listopad JJ, et al., Fas expression by tumor stroma is required for cancer eradication. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2276-81
All references(421)

Other accession IDs

MGD-MRK-11215, MGD-MRK-36230