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Ifngr1
Gene Detail
Symbol

Name
ID
Ifngr1
interferon gamma receptor 1
MGI:107655
Synonyms
CD119, Ifgr, IFN-gammaR, IFN-gamma R, Ifngr, Nktar
Feature Type
protein coding gene
Genetic Map
Chromosome 10
8.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(13)
Sequence Map
Chr10:19591949-19610229 bp, + strand
From VEGA annotation of GRCm38

  18281 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:359  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: interferon gamma receptor
Gene Tree: Ifngr1

Human
homologs
Human Homolog IFNGR1, interferon gamma receptor 1
NCBI Gene ID 3459
neXtProt AC  NX_P15260
Human Synonyms  CD119, IFNGR, IMD27A, IMD27B
Human Chr (Location)  6q23.3; chr6:137197484-137219430 (-)  GRCh38
Disease Associations  (5) Diseases Associated with Human IFNGR1
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a mutant allele exhibit increased susceptibility to viral infection and experimental autoimmune uveoretinitis.
 
Phenotype Images(3)
Interactions
Ifngr1 interacts with 145 markers (Mir17, Mir20b, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cytokine-mediated signaling pathway
Component dendrite, endoplasmic reticulum, ...
Function cytokine binding, cytokine receptor activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (200)    Tissues (13)    Images (48)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 200
cDNA source data(113)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(113) cDNA(113)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000035345 (Evidence)
Ensembl Gene ModelENSMUSG00000020009 (Evidence)
Entrez Gene15979 (Evidence)
UniGene549
DFCITC1593432, TC1575830, TC1673148
DoTSDT.534483
NIA Mouse Gene IndexU011310
Consensus CDS ProjectCCDS35856.1
International Mouse Knockout Project StatusIfngr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035345 VEGA Gene Model | MGI Sequence Detail 18281 C57BL/6J ±  kb
transcript OTTMUST00000090213 VEGA | MGI Sequence Detail 2112 Not Applicable 
polypeptide OTTMUSP00000049447 VEGA | MGI Sequence Detail 477 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(2) UniProt(13)
Polymorphisms
RFLP(1) : SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR008355 Interferon gamma receptor alpha subunit
InterPro IPR021126 Interferon gamma receptor, poxvirus/mammal
Protein Ontology PR:000001361 interferon gamma receptor alpha chain
References
(Earliest) J:8684 Mariano TM, et al., The mouse immune interferon receptor gene is located on chromosome 10. J Biol Chem. 1987 Apr 25;262(12):5812-4
(Latest) J:214430 Althof N, et al., In vivo ablation of type I interferon receptor from cardiomyocytes delays coxsackieviral clearance and accelerates myocardial disease. J Virol. 2014 May;88(9):5087-99
All references(456)
Other
accession IDs
MGD-MRK-11215, MGD-MRK-36230

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory